5b Flashcards
Rule of 4
pH 7.4 +/- 0.04pCO2 40 +/- 4HCO3 24 +/- 4 BE -/+ 4
PaO2 in venous vs arterial samples
venous PaO2 52 arterial PaO2 92
define a mixed acid base disorder
if compensatory response exceeds or falls short of the expected response, a mixed disorder may be present
respiratory disturbances
look at PaCO2decr alkalosisincr acidosis
metabolic disturbances
look at HCO3incr alkalosisdecr acidosis
respiratory acidosis
HYPOventilation (NM or structural diseases, toxins, cervical IVDD, airway obstruction)incr PaCO2compensatory retention of renal HCO3 (usually takes 3-5 days)
respiratory alkalosis
HYPERvent (hypoxemia, lung dz, activation of central reps centers, pain, anxiety)decr PaCO2
avoid hyper ventilation/respiratory alkalosis in what group of trauma patients
HEAD TRAUMA ( hi intracranial P patients)hypervent and low PaCO2 causes cerebral vasoconstrictiondecrease cerebral blood flow
metabolic acidosis
HCO3 decr (loss from kidneys, GI)
anion gap
AG= (Na+K)-(Cl+HCO3)
causes of high AG
Metabolic acidosisK–ketonesL –lactic acidU–uremic acidE–ethylene glycol toxS–salicylate tox
acid base status of addisonian patient
metabolic acidosis with hypochloremia (normal AG)
sodium bicarbonate dosing
to treat metabolic acidosisgoal pH 7.2mEq bicarb = 0.3 x kg x base deficit
metabolic alkalosis
incr HCO3due to loss of Cl (vomiting, suction GI contents, admin diuretics) or gain in exogenous alki
T/F a patient can have concurrent respiratory alkalosis and acidosis
FALSE a patient can have any combo of two primary disorders EXCEPT respiratory acidosis/alkalosis