58 - Chronic Neurological Problems + Lateral Sclerosis Flashcards

1
Q

multiple sclerosis

A

chronic, progressive, DEGENERATIVE DISORDER of the CNS

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2
Q

multiple sclerosis is characterized by…

A

disseminated demyelination of nerve fibers

of brain + spinal cord

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3
Q

parkinson’s

A

chronic, progressive NEURODEGENERATIVE DISORDER

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4
Q

pakinson’s is characterized by

A

bradykinesia + rigidity

  • tremor at rest
  • gait changes
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5
Q

bradykinesia

A

slowness in intitiatn + executn of mvmt

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6
Q

rigidity

A

incr muscle tone

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7
Q

myasthenia gravis

A

autoimmune disease of neuromuscular junction

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8
Q

myasthenia gravis is characterized by…

A

fluctuating weakness of certain skeletal muscle groups

-weakness with increased muscle use

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9
Q

amyotrophic lateral sclerosis

A

rare progressive neuromuscular disorder marked by loss of motor neurons

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10
Q

ALS usually leads to…. in….

A

death in 2-5 yrs after diagnosis

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11
Q

ALS etiology

A

motor neurons in the brainstem + spinal cord gradually degenerate for unknown reasons
-denervation leads to muscle wasting + involuntary contractn

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12
Q

classic signs of ALS

A

progressive muscle weakness + atrophy

-limb onset or bulbar onset

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13
Q

limb onset

A

weakness in arms or legs

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14
Q

bulbar onset

A

slurred speech + problem swallowing

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15
Q

other symptoms of ALS

A
  • pain
  • sleep disorder
  • spasticity
  • hyperreflexia
  • drooling
  • emo lability
  • constipation
  • esophageal reflex
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16
Q

does ALS affect cognition?

A

does not affect intelligence

-pt stays cognitively intact while wasting away

17
Q

most comon cause of death in ALS is due to…

A

compromised respiratory function due to muscle weakness and paralysis

18
Q

exercise to reduce spasticity in ALS

A

-mod-intense endurance type exercise for trunk and limbs

19
Q

adverse effects of leva+carbidopa

A

tardive dyskinesia