58 - Chronic Neurological Problems + Lateral Sclerosis Flashcards
multiple sclerosis
chronic, progressive, DEGENERATIVE DISORDER of the CNS
multiple sclerosis is characterized by…
disseminated demyelination of nerve fibers
of brain + spinal cord
parkinson’s
chronic, progressive NEURODEGENERATIVE DISORDER
pakinson’s is characterized by
bradykinesia + rigidity
- tremor at rest
- gait changes
bradykinesia
slowness in intitiatn + executn of mvmt
rigidity
incr muscle tone
myasthenia gravis
autoimmune disease of neuromuscular junction
myasthenia gravis is characterized by…
fluctuating weakness of certain skeletal muscle groups
-weakness with increased muscle use
amyotrophic lateral sclerosis
rare progressive neuromuscular disorder marked by loss of motor neurons
ALS usually leads to…. in….
death in 2-5 yrs after diagnosis
ALS etiology
motor neurons in the brainstem + spinal cord gradually degenerate for unknown reasons
-denervation leads to muscle wasting + involuntary contractn
classic signs of ALS
progressive muscle weakness + atrophy
-limb onset or bulbar onset
limb onset
weakness in arms or legs
bulbar onset
slurred speech + problem swallowing
other symptoms of ALS
- pain
- sleep disorder
- spasticity
- hyperreflexia
- drooling
- emo lability
- constipation
- esophageal reflex
does ALS affect cognition?
does not affect intelligence
-pt stays cognitively intact while wasting away
most comon cause of death in ALS is due to…
compromised respiratory function due to muscle weakness and paralysis
exercise to reduce spasticity in ALS
-mod-intense endurance type exercise for trunk and limbs
adverse effects of leva+carbidopa
tardive dyskinesia
