58 - Chronic Neurological Problems + Lateral Sclerosis Flashcards
multiple sclerosis
chronic, progressive, DEGENERATIVE DISORDER of the CNS
multiple sclerosis is characterized by…
disseminated demyelination of nerve fibers
of brain + spinal cord
parkinson’s
chronic, progressive NEURODEGENERATIVE DISORDER
pakinson’s is characterized by
bradykinesia + rigidity
- tremor at rest
- gait changes
bradykinesia
slowness in intitiatn + executn of mvmt
rigidity
incr muscle tone
myasthenia gravis
autoimmune disease of neuromuscular junction
myasthenia gravis is characterized by…
fluctuating weakness of certain skeletal muscle groups
-weakness with increased muscle use
amyotrophic lateral sclerosis
rare progressive neuromuscular disorder marked by loss of motor neurons
ALS usually leads to…. in….
death in 2-5 yrs after diagnosis
ALS etiology
motor neurons in the brainstem + spinal cord gradually degenerate for unknown reasons
-denervation leads to muscle wasting + involuntary contractn
classic signs of ALS
progressive muscle weakness + atrophy
-limb onset or bulbar onset
limb onset
weakness in arms or legs
bulbar onset
slurred speech + problem swallowing
other symptoms of ALS
- pain
- sleep disorder
- spasticity
- hyperreflexia
- drooling
- emo lability
- constipation
- esophageal reflex