57. Antifungal drugs Flashcards
1
Q
Groups
A
- Inhibitors of squalene epoxidase:
- Inhibitors of 14alpha-sterol demethylase:
- Inhibitors of fungal membrane stability
- Inhibitors of fungal mitosis
- Cell wall synthesis inhibitor
2
Q
1.Inhibitors of squalene epoxidase:
A
Naftifin (local)
Terbinafine (local)
Terbinafin (systemic)
3
Q
2.Inhibitors of 14alpha-sterol demethylase:
A
Local: Thiabendazole Miconazole Clotrimazole Enilconazole Ketoconazole Posaconazole
Systemic: Itraconazole Fluconazole Posaconazole Voriconazole*
4
Q
3.Inhibitors of fungal membrane stability
A
Local:
Nystatin
Natamycin
Systemic:
Amphotericin-B
5
Q
- Inhibitors of fungal mitosis
A
Systemic:
Griseofulvin
6
Q
5.Cell wall synthesis inhibitor
A
Systemic:
Caspofungin
Micafungin
Anidulafungin
