510-4 Flashcards

0
Q

Basement membrane

A

anchors epithelia to underlying lamina propria. composed of BASAL LAMINA annd RETICULAR LAMINA.

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1
Q

Epithelia

A

one or more layers of closely adhering cells with a BASAL SURFACE and a FREE SURFACE. innervated but not vascular. connected to the lamina propria through a basement membrane.

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2
Q

Basal Lamina

A

mixture of cells produced by the epithelia and fibroblasts. composed of LAMINA LUCIDA and LAMINA DENSA.

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3
Q

Lamina Lucida

A

translucent layer directly below epithelia. contains cells adhesion moleules like LAMININ that binds to type 4 collagen fibers of the lamina densa.

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4
Q

Lamina Densa

A

contains type 4 collagen fibers that are the site of anchoring for the RETICULAR LAMINA

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5
Q

Reticular Lamina

A

collagen and reticular fibers that anchor type 4 collagen fibers of LAMINA DENSA to LAMINA PROPRIA

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6
Q

3 components of a mucous membrane

A
  1. ) epithelia capable of producing mucous
  2. ) lamina propria
  3. ) muscalaris mucosae (smooth muscle)
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7
Q

Transitional epithelia

A

pseudostratified layer of epithelia that appear rounded (domed) and are found in the bladder (stretch when full)

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8
Q

5 types of intercellular junctions

A
  1. ) tight junction (zonula occludens)
  2. ) adhesive junction (zonula adherens)
  3. ) desmosome (macula adherens)
  4. ) gap junctinos
  5. ) hemidesmosomes
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9
Q

tight junction

A

transmembrane proteins (JAM, claudin, occludin) tighly join cells together at the apical region to prevent leakage (quilted pattern)

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10
Q

adhesive junction

A

actin filaments of neighboring cells joined together by cell adhesive molecules (cadherin) and are calcium dependent

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11
Q

desmosome

A

join intermediate filaments of adjacent cells through thr formation of desmosome plaques and cadherin adhesion molecules. holds cells together under mechanical stress (very strong)

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12
Q

gap junction

A

allow for the passage of small, water soluble molecules between cells. CONNEXINS form pores called CONNEXONS.

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13
Q

hemidesmosome

A

anchors intermediate filaments to basal lamina

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14
Q

exocrine gland

A

secretory epethelial gland that empties secretion into ducts

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15
Q

endocrine gland

A

secretory epithelial gland that empties secretion into blood or intracellular fluid

16
Q

2 types of exocrine glands

A

simple- unbranched ducts

compound- branched ducts

17
Q

3 types of exocrine gland shapes

A
  1. ) tubular- secretory glands line the tube of duct
  2. ) acinar- secretory glands in bulbous ACINAR
  3. ) tubuloacinar- secretory glands found in tubes and acinar
18
Q

4 types of glandular secretions

A
  1. ) serous- waters
  2. ) mucous- contains glycoprotein mucin
  3. ) mixed- both serous and mucous cells
  4. ) cytogenic- whole cells released into ducts
19
Q

3 mechanisms of glandular secretion

A
  1. ) merocrine
  2. ) apocrine
  3. ) holocrine
20
Q

merocrine secretion

A

most common type of secretory mechanism. granules exist in vesicles that fuse to the plasma membrane and are released into the duct without a loss of plasma membrane

21
Q

apocrine secretion

A

usually hormonal after puberty is reached. granules are pinched off with plasma membrane and secreted into duct.

22
Q

holocrine

A

cell plasma membrane disintegrates and whole content of cell is released into the ducts