510-4 Flashcards
Basement membrane
anchors epithelia to underlying lamina propria. composed of BASAL LAMINA annd RETICULAR LAMINA.
Epithelia
one or more layers of closely adhering cells with a BASAL SURFACE and a FREE SURFACE. innervated but not vascular. connected to the lamina propria through a basement membrane.
Basal Lamina
mixture of cells produced by the epithelia and fibroblasts. composed of LAMINA LUCIDA and LAMINA DENSA.
Lamina Lucida
translucent layer directly below epithelia. contains cells adhesion moleules like LAMININ that binds to type 4 collagen fibers of the lamina densa.
Lamina Densa
contains type 4 collagen fibers that are the site of anchoring for the RETICULAR LAMINA
Reticular Lamina
collagen and reticular fibers that anchor type 4 collagen fibers of LAMINA DENSA to LAMINA PROPRIA
3 components of a mucous membrane
- ) epithelia capable of producing mucous
- ) lamina propria
- ) muscalaris mucosae (smooth muscle)
Transitional epithelia
pseudostratified layer of epithelia that appear rounded (domed) and are found in the bladder (stretch when full)
5 types of intercellular junctions
- ) tight junction (zonula occludens)
- ) adhesive junction (zonula adherens)
- ) desmosome (macula adherens)
- ) gap junctinos
- ) hemidesmosomes
tight junction
transmembrane proteins (JAM, claudin, occludin) tighly join cells together at the apical region to prevent leakage (quilted pattern)
adhesive junction
actin filaments of neighboring cells joined together by cell adhesive molecules (cadherin) and are calcium dependent
desmosome
join intermediate filaments of adjacent cells through thr formation of desmosome plaques and cadherin adhesion molecules. holds cells together under mechanical stress (very strong)
gap junction
allow for the passage of small, water soluble molecules between cells. CONNEXINS form pores called CONNEXONS.
hemidesmosome
anchors intermediate filaments to basal lamina
exocrine gland
secretory epethelial gland that empties secretion into ducts
endocrine gland
secretory epithelial gland that empties secretion into blood or intracellular fluid
2 types of exocrine glands
simple- unbranched ducts
compound- branched ducts
3 types of exocrine gland shapes
- ) tubular- secretory glands line the tube of duct
- ) acinar- secretory glands in bulbous ACINAR
- ) tubuloacinar- secretory glands found in tubes and acinar
4 types of glandular secretions
- ) serous- waters
- ) mucous- contains glycoprotein mucin
- ) mixed- both serous and mucous cells
- ) cytogenic- whole cells released into ducts
3 mechanisms of glandular secretion
- ) merocrine
- ) apocrine
- ) holocrine
merocrine secretion
most common type of secretory mechanism. granules exist in vesicles that fuse to the plasma membrane and are released into the duct without a loss of plasma membrane
apocrine secretion
usually hormonal after puberty is reached. granules are pinched off with plasma membrane and secreted into duct.
holocrine
cell plasma membrane disintegrates and whole content of cell is released into the ducts