5.1 Cell Membrane Flashcards
A detailed membrane structure was studied only after the advent of the ______ in year ______.
electron microscope; 1950s
The chemical studies on the cell membrane, especially in ___, enabled scientists to deduce the possible structure of the plasma membrane.
Human red blood cells (RBCs)
Cell membrane is mainly composed of ___.
Lipids and Proteins
In the cell membranes, major lipids are _____ that are arranged in a ______.
Phospholipids; bilayer
In a lipid bilayer, the part of lipids that lie:
I. towards the outer side is _____
II. towards the inside side is _____
I. Polar Heads
II. Non-polar Hydrophobic Tails
In lipid bilayer, Non-polar tail of ______ is protected from the ______ environment.
saturated hydrocarbons; aqueous
In addition to phospholipids, Cell membrane also contains __
Cholesterol
Apart from cholesterol and lipids, other biomolecules that make up the cell membrane are _____.
Proteins and carbohydrates
The ratio of ______ and ______ varies in different cell types.
protein and lipid
The membrane of Human erythrocyte has ____ % protein and ____ % lipids.
52%; 40%
Depending on the ease of extraction, Membrane proteins are classified as:
Integral and peripheral proteins
______ proteins lie on the surface, while ______ proteins are partially or totally buried in the membrane.
Peripheral proteins; Integral proteins
The fluid mosaic model is a structure of ______, proposed by ______ in ____ year.
Cell membrane; Singer and Nicolson; 1972
According to the fluid mosaic model,
______ nature of lipids enables ______ movement of proteins within the bilayer.
Quasi-fluid nature; Lateral movement
The ability of the protein to move within the membrane is measured as its _____.
Fluidity
The fluid nature of the membrane is important for functions like:
I. Cell growth
II. Formation of intercellular junctions
III. Secretion
IV. Endocytosis
V. Cell division, etc.
________ is the most important function of the plasma membrane.
Transport of molecules across it
______ is the nature of plasma membrane.
Selectively permeable
The membrane is selectively permeable to all molecules present on either side of it.
T/F
False,
selectively permeable to some molecules
The movement of molecules across the membrane without any energy requirement is called ______.
Passive transport
Movement:
I. Along concentration gradient is-
II. Against concentration gradient is-
I. From higher to lower concentration.
II. From lower to higher concentration
Neutral solutes move across the membrane by the process of ______, which is _______ (along/against) the concentration gradient.
Simple diffusion; along
The movement of water by diffusion is called ______.
Osmosis
______ molecules cannot pass through the nonpolar lipid bilayer.
Polar molecules
______ are required by polar molecules to facilitate their transport across the membrane.
Carrier proteins
A few ions or molecules are transported across the membrane against their concentration gradient is called ______.
Active transport
Active transport is an energy ______ (dependent/independent) process as ______ is utilized.
energy-dependent; ATP
An example of active transport is
Na+/K+ pump