5- The role of clinical guidelines Flashcards
what are clinical guidelines?
Systematically developed recommendations on how healthcare and other professionals should care for people with specific conditions
what are national institute for health and care excellence (NICE) clinical guidelines?
- Systematically developed recommendations on how healthcare and other professionals should care for people with specific conditions
- Based on the best available evidence
what are Scottish intercollegiate guidelines network (SIGN) guidelines?
- Derived from a systematic review of the scientific literature
- Aimed to accelerate the translation of new knowledge into action
- Aim to reduce variations in practice
- Improve patient-important outcomes
Name 3 organisations that produce guidelines.
- British Dental Journal
- European Commission
- General Dental Council (GDC)
How do we rate the quality of a guideline?
- the potential benefits of practice guidelines are only as good as the quality of the guidelines themselves
- it is important to assess the methods used to develop practice guidelines in order to be confident of the resulting recommendations
What should high quality guidelines be?
- based on the best available evidence
- have a clear scope and purpose
- demonstrate methodological rigour
- be free from bias
what is a systemic review?
A replicable, scientific, and transparent process
what do a systemic review do?
A systematic review summarises the results of available carefully designed healthcare studies (controlled trials) and provides a high level of evidence on the effectiveness of healthcare interventions. Judgments may be made about the evidence and inform recommendations for healthcare
What is a benefit of a systemic review?
It reduces researcher bias and demands the researcher is comprehensive in their approach
what are other benefits of a systematic review?
- Can end confusion
- Yield new insights by combining findings from different studies
- Highlights where there is not enough evidence
- When there is enough evidence can reduce the influence of flawed single studies
Name the features of a good systemic review.
- Based on scientifically rigorous methods
- Answers a defined research question
- Searches all relevant sources of peer reviewed published studies and checks for unpublished studies
- Includes and reports pre-established quality control guidelines for studies
- Transparency and replicability of methods
what is the transparency of a systemic review?
- What search terms were used?
- What data sources were searched?
- What studies were excluded and why?
- What period was covered?
- Any conflict of interests?
True or false -A meta -analysis combine the results of individual studies in a systemic review to produce an overall statistic?
True or false - check with someone
what is a meta-analysis?
A meta-analysis combines results of individual studies in a systematic review to produce an overall statistic i.e. the ‘average result’.
what is the aim of meta-analysis?
- Provide a more precise estimate of the effects of an intervention
- to reduce uncertainty