5. Renal blood flow and glomerular filtration rate Flashcards
1
Q
three physical factors that contribute to GFR
A
hydraulic conductivity (permeability/porosity of the fenestrated endothelium) (Lp)
Surface area for filtration (Sf)
Capillary ultrafiltration pressure (PUF)
2
Q
how do you get ultrafiltration coefficient (Kf)
A
hydraulic conductivities (Lp) x surface area for filtration (Sf)
3
Q
GFR equation
A
GFR = Kf * PUF
4
Q
PUF =
A
PGC-PBC-PiGC
5
Q
what role do glomerular mesangial cells play regarding ultrafiltration coefficient
A
glomerular mesangial cells can contract and decrease surface area