5. Palpitations Flashcards

1
Q

conditions that can cause palpitations

A

Cardiovascular: Arrhythmia, cardiomyopathy, hypovolemia
Psychiatric: Anxiety, panic attacks
Medications: Caffeine, stimulants, theophylline, and albuterol use
Substances: Tobacco, caffeine, alcohol intoxication or withdrawal, cocaine
Endocrinologic: Hyperthyroidism, pheochromocytoma, hypoglycemia
Hematologic: Anemia
Infectious: Febrile illness

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2
Q

What are some questions you can ask a patient presenting with palpitations?

A
dizziness or lightheadedness?
chest pain or pressure?
do you feel more hot or cold than others?
any weight changes?
do you drink caffeine?
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3
Q

Signs and Symptoms of Hyperthyroidism

A

Heat intolerance (92%)
Tachycardia (96%) due to increased adrenergic tone and heightened conduction
Fatigue (84%)
Weight loss (50%) due to increased calorigenesis and gut motility causing hyperdefecation and malabsorption.
Tremor (84%)
Increased sweating (96%)
Exertional dyspnea caused by O2 consumption, CO2 production, and respiratory muscle weakness

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4
Q

Which of the following can cause an enlarged thyroid, also known as goiter?

A
Lack of iodine
B  		74.3% 			Hypothyroidism(Hashimoto's)
C  		88.9% 			Hyperthyroidism(Graves)
D  		85.5% 			Nodules
E  		87.2% 			Cancer
F  		51.6% 			Pregnancy
G  		89.5% 			Thyroiditis
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5
Q

Clonus

A

A series of abnormal reflex movements of the foot induced by sudden dorsiflexion causing alternate contraction and relaxation of the gastrocnemius and soleus muscles.

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6
Q

What is the most common cause of hyperthyroidism in adults and children?

A

Toxic diffuse goiter (Graves’ disease)

(60-80%) of hyperthyroidism.

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7
Q

symptomatic relief of adrenergic symptoms in hyperthyroidism

A

Propranolol (beta blocker)

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8
Q

Radioactive iodine uptake (RAIU) test and scan

A

measures the amount and pattern of radioactive iodine taken up by the thyroid in the 24 hours following ingestion of a set dose. Normal RAIU uptake is 15-30% of the ingested dose.

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9
Q

High RAIU (>30%)

A
Graves' disease 	
 Multi-nodular goiter 	
 Toxic solitary nodule 	 
 TSH-secreting pituitary tumor 	
 HCG secreting tumor
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10
Q

Low RAIU (

A
Sub-acute thyroiditis
 Silent thyroiditis
Iodine induced
Exogenous L-Thyroxine
Struma ovarii
Amiodarone
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11
Q

Thyroid peroxidase antibodies

A

present in 70-80% of Graves’ patients

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12
Q

When is a thyroid ultrasound is used ?

A

in the evaluation of thyroid nodules and thyroid enlargement but not hyperthyroidism

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13
Q

Radioactive iodine uptake and scan: diffuse increased uptake in the thyroid gland.

Interpret this result….

A

diffuse uptake in the thyroid gland indicates the entire gland is involved with this synthesis, not just nodular areas. These findings are consistent with Graves’ disease

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14
Q

Autoimmune disease in which thyrotropin receptor antibodies (also called thyroid stimulating immunoglobulins) are produced. These antibodies stimulate the thyroid gland to enlarge and to produce more thyroid hormone.

A

Graves Disease

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15
Q

what are the most common manifestations of Graves’ ophthalmopathy

A

eyelid retraction and exophthalmos.

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16
Q

most commonly used medication to suppress thyroid hormone production.

A

Methimazole

17
Q

serious side effect of Methimazole

A

agranulocytosis

(rare…

18
Q

Oral dose of radioactive iodine

A

During the course of a few months the iodine destroys most of the overactive thyroid cells and the level of thyroid hormone falls and the thyroid gland shrinks in size.

19
Q

Follow-up for Radioactive Iodine Treatment

A

The patient needs to be seen within a few months after her radioactive iodine treatment to see when to discontinue propranolol (if prescribed) and to follow her TSH. The patient should have her TSH drawn every two to three months until it has stabilized.

20
Q

Patient may come back hypo because iodine destroyed too much of the thyroid….in that case you have to…

A

start on thyroid replacement

Levothyroxine

21
Q

starting dose of thyroxine in primary hypothyroidism

A

1.5-1.8 mcg per kilogram.

22
Q

When a stable TSH level has been achieved, how often should you check levels?

A

TSH can be checked once or twice annually