5 - Otolaryngology Flashcards
The 3 Pharynges
Nasopharynx
Oropharynx
Hypopharynx
Mouth disease list
Leukoplakia Erythoplakia Oral lichen planus Oral cancer Oral herpes Candidiasis Glossitis Intraoral lesions Disease of teeth/gums
Throat diseases list
Pharyngitis and tonsilitits
Peritonsillar abscess and cellulitis
Tonsillectomy
Diseases of the salivary glands list
Sialandenitis
Parotitis
Key to success for diagnosing oral lesions?
Form an appropriate differential diagnosis based on H/P
Even longer list of oral cavity lesions?
Slide 8
What is the problem with precancer and early oral cancer?
They are subtle and often asymptomatic
Presentation of early and precancer?
White/red patch
- Progresses to ulceration
- Becomes endophytic or exophytic mass (SCC)
Endophytic vs exophytic?
Endophytic - grows inward from superficial lesion
Exophytic - grows outward from the lesion
Best known precancerous oral lesion?
Leukoplakia - precancer
What is leukoplakia?
Precancer
white patches or plaques
- non-removal
Represents hyperplasia of the squamous epithelium
Transformation of leukoplakia?
Hyperplasia -> dysplasia -> carcinoma in situ -> invasive malignant tumor
Leukoplakia progression to cancer?
1-20% become cancer in 10 yrs
What (non-cancer) causes leukoplakia?
Inflammatory conditions
- hyperkeratosis from chronic irritation (dentures, tobacco etc)
What is erythroplakia?
Similar to leukoplakia except red (erythematous for your smart people)
Problem with erythroplakia?
More likely than leukoplakia to exhibit dysplasia or carcinoma microscopically
- 90% are dysplasia/SCC
Exam for leuko/erythroplakia?
Through oral exam
Palpation of neck for lymphadenopathy
Biopsy everything
When should you give an ENT referral for leuko/erythro?
Early
- precancer needs to be removed
- cryotherapy and lasers are used sometimes but not preferred
MC oral cancer?
Squamous cell carcinoma SCC
-90% of oral cancer
Describe SCC
Ulcers or masses that dont heal
Any persistent lesions in mouth need?
Biopsy and ENT referral
Risk factors for SCC?
Tobacco/ETOH
- accounts for 80%
Combine them and they are even more effective
Common locations of SCC?
Ventral surface of tongue
Hard palate
Tip of tongue
Mouth hole
5 yr survival SCC?
5 yr = 50-55%
ABCDE of melanoma?
A - assymetry B - Boarders (irregular) C - color (variable) D - Diameter (increased) E - elevation
DDX for melanoma?
Melanosis - symmetric spots on dark skin ppl
Oral melanotic macules - symmetric w sharp boarders
Amalgam tattoos - leeching of dental fillings
What are fordyce spots?
Benign neoplams of sebaceous gland etiology
- isolated/scattered
- white/yellow,
- 1-2mm discrete papules
Prominent on vermillion/buccal mucosal boarder
What are mucoceles?
Fluid filled caveties in mucous glands
- after mild oral trauma
Mucoceles MCC?
MCC - lower lip biting
Tx for mucoceles?
Symptomatic - cryotherpathy/excision
Aspiration may relieve symptoms but usually come back
Oral linchen planus are?
Chronic waxing and waning inflammatory condition
Maybe immune mediated
Usually pts >40yo
Forms of oral lichen planus?
2 clinical forms
Reticular
- white, lacy striations (wickham’s striae) or papules on buccal mucosa
- painless
Erosive
- zones of tender erythema and painful ulcers surrounded by white radiating straie
Thrush?
Oral candidiasis
What is candidiasis?
Fluctuating mouth or throat discomfort caused by fungus
- seen in young and AIDS
Describe thrush
Erythema of oral cavity
Creamy-white curd-like patches
Angular chelitis
Resolves rapidly w tx
Causes of etiology?
MC - candida albicans
Less common
- C glabrata
- C. Krusei
- C. Tropicalis
Forms of oral candidiasis?
Pseudomembranous form: MC
- overall-white plaques on buccal mucosa, palate, tongue or oropharynx
Atrophic form (denture stomatitis):
- MC in older adults
- erythema w/o plaques
Diagnosis of candidiasis?
KOB - budding yeast
Aids test
Candidiasis tx in infants
Topical antifungal
- nystatin suspension x 2 weeks
- gentian violet/oral fluconazol if refractory
Sterilizing bottles/nipples