5. Multiple Organ Dysfunction Syndrome (MODS)

Question 1

Multiple organ dysfunction syndrome (MODS) is sometimes referred to as

Answer 1

multiple organ dysfunction syndrome. MODS is the progressive insufficiency of 2 or more organs in an acutely ill pt, such that homeostasis cannot be maintained w/out intervention (Table 5-6)

Question 2

CV Markers of MODS

Answer 2

-Hypotension
-Tachycardia
-Dysrhythmias
-Need for vasopressor support
-Decreased systemic vascular resistance
-Abnormal CVP (low or high)
-Positive Troponin

Question 3

Pulmonary Markers of MODS

Answer 3

-Tachypnea
-Dyspnea
-Hypoxemia

Question 4

Neurological Markers of MODS

Answer 4

-Confusion
-Delirium
-Disorientation
-Lethargy, coma
-Seizure

Question 5

Renal Markers of MODS

Answer 5

-Elevated creatinine
-Decreased GFR
-Oliguria
-Life-threatening electrolyte imbalances

Question 6

Hepatic Markers of MODS

Answer 6

-Elevated liver enzymes
-Hypoglycemia
-decreased albumin
-jaundice

Question 7

Hematologic Markers of MODS

Answer 7

-Thrombocytopenia
-coagulopathy
-increased D-dimer levels
-decreased protein C levels

Question 8

Endocrine Markers of MODS

Answer 8

-hyperglycemia or
-hypoglycemia
-adrenal insufficiency

Question 9

Metabolic Markers of MODS

Answer 9

-Metabolic acidosis
-Elevated lactate

Question 10

MODS may be the result of

Answer 10

any type of shock
-the greater the number of organs involved, the
higher the mortality.
-Accounts for ~ 80% of all ICU deaths annually