5. intro to reproductive system Flashcards
label diagram of reproductive tract
ovaries
Fallopian / uterine tubes
- fimbriae
- infundibulum
- Ampulla
- Isthmus
Uterus
- perimetrium
- myometrium
- endometrium
Cervix
vagina
Describe components of perineum
- anal tringle
- anal passage + sphincter
- Urogenital triangle
- Vulva (external genitalia)
- urethral orifice
- vaginal orifice
- labia majus and minus
- vestibule + vestibular glands
- clitoris
- Vulva (external genitalia)
describe the pelvic floor
muscular sling at outlet of pelvic girdle
supports internal structures of pelvic cavity
briefly describe function of ovaries
- composed of oocytes and follicular cells
- site of oogenesis (primary oocyte becomes secondary oocyte)
- release of secondary oocyte each month (ovulation)
- synthesis of oestrogen + progesterone (these help maintain early pregnancy
- regulated by Luteinising Hormone and Follicle stimulating Hormone (from Anterior Pituitary, which is regulated by Hypothalamus)
briefly describe function of uterine tubes
extend over each ovary to the uterus
Transport- fertilised ovum / oocyte to uterus
briefly describe function of uterus
- receives and nourishes fertilised ovum / embryo / fetus
- made up of three parts
- Fundus (most superior portion)
- body (site of implantation, area of growth and expansion to accomodate baby)
- cervix (most inferior portion)
- uterus wall is made up of 3 layers
- Perimetrium (serous membrane)
- myometrium (thick layer of smooth muscle)
- endometrium (epithelial cells- regulated by ovarian hormones)
- functional layer
- basal layer
describe role of cervix
protection (protect pathogens getting into upper reproductive tract)
secrete mucus to support fertilisation
allows passage of baby / menstrual blood
briefly describe function of vagina
receives penis + ejaculate
forms birth canal
briefly describe function of mammary glands
exocrine glands- secrete to body surface via a duct
- produce and secrete colostrum and breastmilk
- stimulated by both hormones and suckling
Describe ovarian cycle
two components
- 28 day cycle that begins at puberty - menopause
- regulated by Hypthalamus (GnRH) and Anterior Pituitary (LH + FSH)
- oogenesis
- development of female gamete (egg /ovum)
- development of follicles
- Follicles house oocytes and enable release of secondary oocyte from ovary
- follicles produce and release oestrogen + progesterone
3 phases
-
Follicular phase (day 1-13)
- Follicle develops from primary follice → secondary follicle → Graafian follicle (mature) - stimulated by FsH
- Follicles release ostrogen
- Primary oocyte completes meiosis I to become secondary Oocyte (haploid (n)), and starts + halts meiosis I - stimulated by LH
- Follicle develops from primary follice → secondary follicle → Graafian follicle (mature) - stimulated by FsH
-
Ovulation (day 14)
- Primary oocyte released out of ovary
-
Luteal phase (day 15-28)
- Remaining follicles become Corpus Luteum and release Progesterone and Oestrogen
- progesterone and Oestrogen continue negative feedback on Hypothalamus / Anterior Pituitary
- Progesterone maintains endometrium
- Corpus luteum degenerates into Corpus Albicans if fertilisation doesn’t occur
- if fertilisation does occur, corpus luterum remains, and continues to secrete progesterone and oestrogen until placenta can take over
- Remaining follicles become Corpus Luteum and release Progesterone and Oestrogen
describe uterine cycle (menstrual cycle)
3 phases
- menstrual phase (day 1-5)
- shedding of endometrial uterine layer (functional layer)
- triggered by drop in progesterone with degeneration of corpus luteum
-
proliferative phase (day 6-14)- regulated by oestrogen
- Proliferation of endometrial cells - stimulated by oestrogen from developing follicle
- growth/enlargement of glands
- increase in blood supply via growth of spiral arteries
- thinning of cervical mucus / forming channels within the mucus
-
secretory phase (day 15-28) - largely regulated by progesterone
- Continued proliferation of endometrial cells (stimulated by ongoing oestrogen)
- Continued growth of glands, and secretion of glycogen which will nourish early embryo
- continued increase in blood supply
- stimulate mucus to thicken and form a mucus plug
-
If ovum is not fertilised
- degeneration of Corpus Luteum results in drop in progesterone, and spiral arteries kink and spasm, reducing blood supply to functional layer, and result in cell death
-
If ovum is fertilised
- Corpus luteum continues to release progesterone, and blood supply continues to increase / endometrial layer continues to grow / Glycogen continue sto be secreted
- cervical mucus remains thick with plug formation
-
If ovum is not fertilised
describe oogenesis
Process to mature primary oocytes into sex gametes (ovum).
involves both mitosis and 2 meiosis divisions- results in daughter cells that have ½ the chromosomes of the parent cell
- female is born with millions of primary oocytes (2n, diploid) that have divided via mitosis in vitro
- pre-puberty, many primary oocytes die / kill themselves
- at puberty, every month
- 1 primary oocyte undergoes Meisis I in follicular phase (stimulated by LH)- becomes Secondary Ooocyte (haploid, n)
- Starts and halts Meiosis II
- If fertilisation occurs, Secondary Oocyte completes meiosis II, to become ovum / egg
- up to 4 polar bodies are created
describe follicular dev (not examinable)
What are the four components of the uterine tube
fimbriae
infundibulum
ampulla
isthmus
what is the fimbriae, where is it located
finger like projections from the infundibulum
fimbriae sweep the ovulated oocyte into the infundibulum