5-HT Drugs And Disease Flashcards by Samuel Jones | Brainscape

Q

What drugs affect storage of 5-HT?

A

tetrabenazine (reserpine)

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Q

What drugs affect 5-HT synthesis?

A

p-chlorophenylalanine (TH inhib)

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Q

What full agonists of 5-HT do you know?

A

5-HT

sumitriptan (5-HT1D)

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Q

Partial agonists of 5-HT?

A

buspirone (5-HT1A)

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Q

Antagonists of 5-HT?

A

ondansetron (5-HT3)

ketanserin (5-HT2A)

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Q

What drugs affect reuptake of 5-HT?

A

SSRI (citalopram),
TCAs (imipramine)
amphetamine

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Q

What drugs affect 5HT degradation?

A

MAOI (phenelzine)

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Q

What recreational drugs related to 5-HT?

A

Amphetamines and derivatives (e.g. MDMA)
LSD
Mescaline
Psilocybin (magic mushrooms)

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Q

What diseases are 5-HT involved in?

A

Depression
Anxiety
Migraine
Hallucinations

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Q

What are the functions of 5-HT?

A

Mood
Body temp control
Sleep wake cycle
Appetite

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