5 Drug Discovery Flashcards
1
Q
What are the three steps of fragment-based combinatorial chemistry?
in drug design
A
1 - synthesis of building blocks
2- generation of combinatorial libraries
3 - activity screening with drug and protein
2
Q
What is phenotypic screening?
A
test of small molecules that alter phenotype
3
Q
What is virtual screening?
A
computer based docking of small moelcules with homology models of teh biological target
