5. Communicating Information

Question 1

Ramipril [1]

Answer 1

Teratogenic - should give labetolol if planning/pregnant

Question 2

Tamoxifen [4]

Answer 2

• Increases risk of endometrial cancer
• Can cause hot flushes
• Increases effectiveness of warfarin
• Increases risk of VTE

Question 3

Sulphonylureas (e.g. gliclazide) [3]

Answer 3

• Can cause hypos
• Should be given in morning with meals
• Should not double up dose if missed

Question 4

Methotrexate [4]

Answer 4

• Regular WCC monitoring needed
• Once weekly dosing
• Folate antagonists (e.g. trimethoprim) shouldnt be given with it
• Folate should be prescribed with it

Question 5

Warafin [3]

Answer 5

• Carries significant risk of bleeding
• Initially weekly bloods > progress to montly
• Different doses have different colours

Question 6

Alendronic Acid [4]

Answer 6

• Should be taken with big glass of water + sit upright
• Once weekly dosing
• Should be taken on different day to bisphosphonates
• Don’t eat for 2+ hours after taking

Question 7

SSRIs [4]

Answer 7

• Takes several weeks to work
• Need to still warn about suicidal ideation
• Can cause dry mouth
• Dont stop suddenly
• Risk of serotonin syndrome - nausea, vomiting, temp