5. Cancer Flashcards

1
Q

8 hallmarks of cancer ?

A

GF independence or self-sufficiency.
Insensitivity to anti-growth signals.
Avoidance of programmed cell death.
Ability to recruit blood supply.
Immortilization by reactivation of telomerase.
Ability to invade adjacent normal tissues and metastases in distant sites.
Reprogrammed energy metabolism.
Evading immune destruction.

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2
Q

What is telomerase ?

A

Maintains chromosome life - without, chromosomes fray over time and cells eventually stop dividing.

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