5 - Amblyopia Studies II Flashcards
Optical correction for anisometropic amblyopia
- results
- notes: outcome was related to __, with most resolution occurring with __
- conclusion
Amblyopia
- improved in 77%
- resolved in 27%
- most seen in 15 weeks
Better baseline VA/lesser aniso, most in cases with 20/40-20/100
Refractive correction alone improves ~25% of children <7 yo with anisometropia
Patching vs atropine kids 7-12 yo
-conclusion
Tx with atropine or patching 2 hrs/day had similar improvement in moderate amblyopia
~20% achieved VA >20/25 in amblyopic eye
Near activity with patching
-conclusion
Does not improve VA, however many still do out of habit or as incentive
Weekend atropine with plano lens vs atropine alone
-conclusion
Augmentation of one drop of weekend atropine with a plano lens does not substantially improve amblyopic VA vs atropine alone (don’t do)
Patching vs Bangerter occlusion filter
- notes: treatment burden, compliance, stereoacuity
- conclusion
Lower tx burden in filter group (can change density) Compliance better (?) No diff b/w tx groups in stereo
Bangerter filter is a reasonable option for initial tx of moderate amblyopia
Intense final push of patching and atropine
-conclusion
Discontinued study
Did not give a better VA outcome after 10 weeks
Effect of optical correction alone on amblyopia
- notes: alignment, hypothesis for VA improvement, time course
- conclusion
VA improved regardless of alignment (importance of correction) 1) improvement in alignment 2) improved retinal image clarity 50% best VA by 9 weeks 90% by 18 weeks All by 45 weeks
Resolves ~25% without need for add’l tx = consider before other therapies
Incr daily patching for residual amblyopia
-conclusion
When VA stops improving with 2 hrs of daily patching, incr to 6 results in more improvement after 10 weeks vs staying at 2 hrs
Levodopa as tx for residual
-main point
Does not produce improvement
VA improvement in binocular activities vs patching
-conclusion
Not as good as 2 hrs of patching daily
