4A - DNA, RNA And Protein Synthesis Flashcards
Eukaryotic DNA
- Linear DNA - chromosomes
- long and wound up
- wound around proteins called histones
- histones help to support the DNA
- coiled up tightly to make a compact chromosome
Mitochondria and chloroplasts have own dna
Prokaryotic DNA
Shorter and circular
- also carry chromosomes
- no histones
- condensed by supercoiling
DNA contains genes
Gene= a sequence of DNA bases that codes for a polypeptide or functional RNA
- sequence of amino acids forms the primary structure of a protein
- different polypeptides have a different number and order of amino acids. It’s the order of the bases in a gene that determines the order of amino acids in a polypeptide
How is an amino acid coded for
By a sequence of 3 bases called a triplet
First stage of protein synthesis
DNA is copied into mRNA
Functional RNA
Genes that don’t code for a polypeptide code for functional RNA instead. Which is rna molecules other than mRNA whcih perform special tasks during protein susnthesis
tRNA
rRNA
Genome
Complete set of genes in the cell
Proteome
Full range of proteins that the cell is able to produce
Introns
- the section of some genes that do code for polypeptides contain sections that’s DONT code for amino acids
- can be several within a gene
Removed during protein synthesis so they don’t affect the amino acid order
Only in eukaryotes
Exon
Bit of gene that does code for an amino acid
Non coding repeats
Regions of multiple repeats
DNA sequences that repeat over and over
-don’t code for amino acids
CCTTCCTTCCTT
Alleles
Genes can exist in more than one form
= different versions of the same polypeptide
- due to order of bases in each allele
About homologous chromosomes
23 pairs of chromosomes
Pairs of Matching chromosomes
Both chromosomes are the same size and have the same GENES , although the could have different alleles
Locus
Fixed position where alleles coding for the same locus on each chromosome in a homologous pair
mRNA
- made during transcription
- carries genetic code from DNA to ribosomes, where it’s used to make a protein during translation
- single polynucleotide strand