Drugs

Question 1

What are the major side effects of ACE inhibitors that patients must be informed of?

Answer 1

Dry cough

Angioedema

Question 2

What is the major side effect of carbimazole that you must be wary of?

Answer 2

Agranulocytosis (acute, severe neutropenia)

Question 3

What type of drug is endone? What dose is used in chronic pain?

Answer 3

Oxycodone

2.5-5mg

Question 4

What is the mechanism of action of the combined oral contraceptive pill?

Answer 4

Negative feedback by progesterone on the hypothalamus causes reduced secretion of GnRH. This in turn causes reduced secretion of LH and FSH. Low FSH prevent follicular development and secretion of estradiol. Progesterone negative feedback + the absent of estradiol means there is no LH surge. So finally, the lack of follicular development and the LH surge prevents ovulation

Question 5

When should aspirin be used for it’s protective affects in CVD?

Answer 5

It should only be used in patient with known CVD, cerebrovascular disease or other vascular disease

The benefit of its use in patients without those do not out weigh the risks of using it