45 Sys complment Flashcards

1
Q
  • C1 reconnait FC de quel IG?
A

M et G

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2
Q
  • Quel sonts le c3 convertases de la voie classique et la voie alterne( stabilisé par quoi?)
A

CLAS C4bC2b

c3 convertase alterne d’amplification … C3bBb

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3
Q

quels sont les complexes c5 convertases des voies classiques et alternes

A

CLAS C4b2bC3b

c5 convertase alternative … C3bBbC3b

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4
Q

quels sont les initiateurs de chaque voie?

A

-clas C1… fc Ig m Igg > c1 esterase
Alterne C3
Lectine MBL Mannose binding lectine Protein

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5
Q

voi de lectines?

A

-MBL initiateur reconnaît résidus glucidiqus (mannose) donnent une enzyme MASP 1 et 2

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6
Q

phase terminale?

A

-c5 activé se lie a la cell cible et induit la fixation de. C5 6 7 8 qui vont induire lla polymerisation de C9 -> pore transm hydrophiles et destruction osmotique

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7
Q

fonctions du complement

A

P Opsonisztion C3b
I Anaphylatoxique -> degranulation masto et TAXI chimiotactisme
Machine gun complexe d attaque membranaire pr la cytolyse memebranaire

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8
Q

Quest ce qui stabilise la c3 conv alterne

A

Pro Per Dine

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