12.1 secretion biliare Flashcards

1
Q

bile caracteristiqye? debit

A
  • ph neutre, jaune verdatre, 0,5 l à 1l
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2
Q

role?

A
  • absorption digestion

detoxification de composans comme l amoniac, lesmedicaments, bilirubine… sont exo et endo

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3
Q

composition double, quoi?

2eme tpye de compo, ya 2 sous types lesquelles?

A

-hydro electro = plasma
- organique
—bilirubine (l heme … biliverdine.. urobilinogene…)
— lipides
*cholesterol
*
*acides biliaire (sels biliaires)

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4
Q

secretion biliaire autre nom?

A
  • cholérèse
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5
Q

roles des acides bilaires?

A
  • inhibition de la reabsotion d eau et d electrolytes dans le colon
  • detergents –> chol et phospholipides solubles
  • choleretiques … declenchent et maintiennet
  • ## absorption des lipides facilités,, solubulisation par micelles sou forme de goutellettes
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6
Q

secretion bilaire vs excretion

A

-secretion continue / excretion discontinue

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7
Q

2 mecanisme de cholerese

A
  • canaliculaire (synthese)

ductulaire (secretion hydro electrolyt -> dilution et ph augmenté

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8
Q

regualtion de cette secretrion

A

-CCK, gastrine (cck like)

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9
Q

2 phases de l’exrection? se font comment? stimulation?

A
  • phase 1 -> remplissage de la vb -> sphincter d oddi fermé car pression basse (moins de 25cmh2o) -> bile remonde dans le cystique…. vb augmente de vol mais pas de pression
    phase 2 -> excretin -> contraction du choledoque -> ouverture d oddi…
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10
Q

Sels biliaires .. leurs synthese?
les elimines sont 1aire 2 ou 3?
2daires comment et ou?

A

ab 1aire: foie
2ere: decinjugaison dans l intestin des 111
3aire.. reconjugaison des 2ere reabsrbes
les elimines sont les 5% des 15% des secondaires
5% slmnt doit etre synthetisees…
85% reabsorbe… as 1aire -> FOIE

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