4.13 Micro Slow CNS Infections Flashcards

1
Q

what causes SSPE? How does it present?

A
  1. Occurs 7-10 years after natural measles infection. usually in children
  2. Initially, mild changes in personality -> proceeds over months - years to generalized convulsions, dementia and death
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2
Q

how is SSPE diagnosed?

A

Measles antibody detected in CSF, electroencephalography

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3
Q

what virus causes PML?

A

JC virus: a polyomavirus, which are small, circular dsDNA, non-enveloped & cytolytic

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