4.1 Stereoisomerism Flashcards
1
Q
What is optical isomerism?
A
- 4 different carbon groups attached to the same carbon atom
- non-super improbable mirror image of a molecule
2
Q
What differentiates R or S enantiomers
A
- when polarises light is shone at enantiomers they respond differently
- R rotates right and S rotates left
3
Q
What is meant by a racemic mixture?
A
A 50-50 split of enantiomers
4
Q
What makes something optically active?
A
It being an optical isomerism
5
Q
What are 2 benefits of using single stereoisomers in drug synthesis?
A
- no health harms as no R or S enantiomers
- higher yield
- cheaper as R and S separation is expensive (chiral pool synthesis )