4. Respiratory Embryology Flashcards
What pharyngeal arch develops into the lungs?
Sixth pharyngeal arch
What layer gives rise to the cartilage, smooth muscle, and connective tissue of the respiratory system?
Splanchnic mesoderm
In what week is the laryngotracheal diverticulum forming?
4th week
During what week do the tracheoesophageal septa close, forming the trachea and esophagus?
5th week
What embryological structure gives rise to the laryngeal cartilage?
Neural crest cells
What swellings of neural crest cells become the laryngeal cartilages?
Arytenoid swellings
In what week does recanalization complete?
By the 10th week
What eminence gives rise to the epiglottis?
Hypobranchial / Hypopharyngial eminence
What defect is caused by a failure of recanalization?
Laryngeal atresia
What are 85% of cases of tracheoesophageal fistulae associated with?
Esophageal atresia
In what stage of lung development do we start to see respiratory bronchiole?
Canalicular Stage
What weeks make up the canallicular stage?
Week 16 - 25
What weeks make up the terminal sac stage?
24 weeks to Birth
What weeks make up the alveolar stage
32 weeks to 8 years
When do we see surfactant being produced?
Terminal stage
