4 - Nerves Flashcards

1
Q

a lot of _____ praise from the brainstem

A

cranial nerves

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2
Q

the brainstem is primarily made up of _____ matter

A

grey

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3
Q

Structurally, what is the cerebellum?

A

hindbrain structure attached to the brainstem

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4
Q

Where are unipolar cells found in the NS?

A

(Rarely found in the CNS)

around the retina

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5
Q

What is a pseudo-unipolar cell and where is it found in the NS?

A

has a single axonal projection which splits into two
rarely found in the CNS
mainly found in the pain pathway in the PNS

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6
Q

What is a bipolar cell and where is it found in the NS?

A

two projections - 1 axon and 1 dendrite

rarely found in the CNS

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7
Q

What is a multipolar cell and where is it found in the NS?

A

numbers projections coming form the cell body - 1 axon and multiple dendrites
very common
have many morphologies

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8
Q

What are the three types of multipolar cells? Where are they found?

A

Pyramidal, Golgi and Purkinje

Pukinje and Golgi are the GABA neurones found in the cerebellum

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9
Q

Where does an axon originate from?

A

the soma at the axon hillock

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10
Q

What can axons branch into?

A

collaterals

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11
Q

Give some characteristics of neurones

A
  • excitable cells
  • heterogenous morphology
  • non-dividing cells
  • 3 parts: soma, axon and dendrites
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12
Q

are dendrites myelinated?

A

NO

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13
Q

What is neuroglia/glia?

A

the connective tissue of the nervous system, consisting of several different types of cell associated with neurons
(all other cells of the NS except neurones)

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14
Q

What is the most abundant cll type in the mammalian brain?

A

astrocytes

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15
Q

What is the main difference between oligodendrocytes and schwann cells?

A

one oligodendrocyte myelinated many axons
one Schwann cell myelinated one axon segment

oligodendrocytes - in the CNS
schwann cells - in the PNS

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16
Q

What are ependymal cells and what is their function?

A

the epithelial cells of the CNS

they line fluid filled ventricles and regulate production and movement of cerebrospinal fluid

17
Q

Compare the concentration of chloride ions intracellularly and extracellularly

A

higher extracellular concentration

18
Q

Compare the concentration of calcium ions intracellularly and extracellularly

A

in very low concentrations
higher extracellularly
very steep concentration gradient

19
Q

What properties of myelin prevent the spread of an AP?

A

high resistance

low capacitance

20
Q

Give the sequence of events of neurotransmission at a synapse

A
  • when the AP arrives the the presynaptic membrane, depolarisation causes the opening of VGCCs, leading to an influx of Ca2+
  • Ca2+ causes vesicular exocytosis
  • neurotransmitter binds to receptors on the post-synaptic membrane
  • neurotransmitter reuptake:
    1 - metabolised by enzymes in the synaptic cleft and taken back up by the axon terminal
    2 - recycled by transporter proteins