4 Genetic information, variation and relationships between organisms Flashcards
Name the fixed position occupied by a gene on a DNA molecule. (1)
Locus/Loci
Describe how a gene is a code for the production of a polypeptide. Do NOT include information about transcription and translation in your answer. (3)
The gene’s base sequence is read in triplets, which determines the order of the amino acid sequence in the polypeptide.
Define the term exon. (1)
The base sequence coding for a sequence of amino acids.
Describe how a phosphodiester bond is formed between two nucleotides within a DNA molecule. (2)
There is a condensation reaction between the phosphate group and the deoxyribose sugar. This reaction is catalysed by DNA polymerase.
Name the protein associated with DNA in a chromosome. (1)
Histone.
Define ‘non-coding base sequences’ and describe where the non-coding multiple repeats are positioned in the genome. (2)
Non-coding sections are DNA which do not code for an amino acid sequence.
They are positioned between genes.
Give three ways in which the DNA in a chloroplast is different from the DNA in a nucleus. (3)
- In chloroplasts, DNA is shorter whereas in the nucleus, DNA is longer.
- In chloroplasts, the DNA is circular whereas in the nucleus it is linear.
- In chloroplasts, the DNA is not associated with histones whereas in nuclear DNA it is.
Other than the uracil base in place of thymine, give one other difference between the structure of a DNA nucleotide and the structure of an RNA nucleotide. (1)
DNA has deoxyribose sugar and RNA has ribose sugar.
Not all mutations in the nucleotide sequence of a gene cause a change in the structure of a polypeptide. Give two reasons why. (2)
- Triplets code for the same amino acid (degenerate)
- They can occur in the non-coding sequence.
Compare and contrast the DNA in eukaryotic cells with the DNA in prokaryotic cells. (5)
Nucleotide structure are identical in both.
Their nucleotides are joined by phosphodiester bonds.
Eukaryotic DNA is longer than prokaryotic DNA.
Eukaryotic DNA is linear, prokaryotic DNA is circular.
Eukaryotic DNA is associated with histones, prokaryotic DNA is not.
What is a homologous pair of chromosomes? (1)
Two chromosomes that carry the same genes.
What is the bond between complementary base pairs in a DNA molecule? (1)
Hydrogen bond.
What is the bond between adjacent nucleotides in a DNA strand? (1)
Phosphodiester bond.
Describe two differences between the structure of a tRNA molecule and an mRNA molecule. (2)
- tRNA is a ‘clover leaf’ shape, mRNA is linear.
- tRNA has an amino acid binding site, mRNA is not.
Describe and explain a difference in the structure of mRNA used in translation and pre-mRNA molecules. (2)
mRNA has no introns, only exons. pre-mRNA has both introns and exons. This is due to splicing.