4 — body comp + diabetes Flashcards

1
Q

Metabolic syndrome
(MetS or Metabolic X)
[basics]

A

: Coexistence of visceral fat, imparied fasting glucose, or overt diabetes Mellitus
- Reduced HDL
- Increased BP
- Triglyceride

[not a clear definition, but used to define the presence of these]

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2
Q

MetS diagnosis

A
  1. Central obesity
    ≥ 94cm for men
    ≥ 80 cm for women
  2. TWO of these
    - Raised TG level (≥150mg/dL)
    - Reduced HDL (men <40 mg/dL, women <50mg/dL)
    - Raised BP (SBP≥130, DBP ≥85)
    - Raised fasting plasma glucose (FPG) (≥100mg/dL)
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3
Q

MetS prevention and treatment

A
  • Movement and diet!
  • HDL
  • Minimize processed foods + sugar
  • Loose weight
    –> Weight loss surgery (bariatric surgery)
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4
Q

Overweight and obesity

A

The proportion of total body weight that is fat

Overweight: above the recommended range
Obesity: more serious degree of overweight (health risks)
30 BMI

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5
Q

Body composition

A

: relative amount of fat mass and fat-free mass
(FFM = Bone, water, muscle, CT, organs, and teeth)

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6
Q

Essential fat

A

Crucial for normal functioning
Men = 3-5%
Women = 8-12%
Non-essential fat = adipose tissue
Visceral organs, subcutaneous

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7
Q

Fat-free body mass index

A

: amount of muscle mass relative to height

Total body fat = weight * (body fat% / 100)
Lean weight = weight * (1-(body fat % / 100))
FFMI = (lean weight/2.2) / ((feet + 12.0 + inches)*(0.0254)2

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8
Q

Problems with low-fat level + muscle mass

A
  • Reproductive, circulator, and immune disorders
  • RED-s (relative energy deficiency in sports)
  • More in endurance sports
  • Not enough calories => performance drops
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9
Q

Ways of Estimating Body Composition

A

Caliper/skinfold
Thickness are measures + summed to find average
Calculations
Human error

Underwater weighing
Percentages of fat/fat-free weight
Body density (water displacement)

Bod pod
Air displacement

Bioelectrical impedance analysis (BIA)
Electrical current sent through body
Resistance can determine body comp

DEXA (dual-energy X-ray Absorptiometry)
Body scan

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10
Q

Obesity + T2D

A

Glucose allostasis: less insulin produced by B cells in the pancreas

  • Desensitizes GLUT transporters
    (Muscle cell surface, gates, physical change => increased blood glucose)
  • Abdominal produce “pro-inlammatory”
    => less sensitive to insulin

Low adiponectin (= fat burner)
- Increases with exercise

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11
Q

Diabetes mellitus

A

disruption of normal glucose metabolism

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12
Q

Type 1 diabetes (definition)

A

Pancrease produced too little or no insulin (auto-immune)
- Genetic or viral

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13
Q

Type 2 diabetes (definition)

A

Pancreas doesn’t produce enough (and/or) resistance to insulin

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14
Q

Gestational diabetes

A

2-5% of pregnant women

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15
Q

Pre-diabetes

A

elevated blood glucose levels

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16
Q

Diabetes — saturated fat

A

Cell membrane composition
Inramyocellular lipids form in muscle cells
=> affecting receptors => sensitivity decrease
(blocks insulin-signalling process)

17
Q

Diabetes testing

A

Blood sample

18
Q

Acute diabetes blood sample

A
  • Fasting glucose test
  • Oral glucose tolerance test
  • Random glucose test
  • Urine sample
    • Shouldn’t have glucose/ketones
    • If present, means using fatty acids NOT glucose
19
Q

Type 1 — insulin

A

Lower glucose within 30 mins
Peak effect = 2-5 hours after
High intensity training = increased sugar levels => hyperglycemic
Low intensity training = decrease => hypoglycemic

20
Q

Type 1 — Physiological effects of exercise

A

Increase adiponectin
Decrease pro-inflam chemicals
Decreases high sensitivity-c reactive protei (measures inflammation)
Decreased HbA1c (~5% ideal)

21
Q

Type 1 — FITT (cardio)

A

HIIT/Weight training (keep in mind hyperglycemia)
Moderate aerobic (keep in mind hypoglycemia)
F = daily, help glucose control
I = 60-90% of max HR
20-60 min/week
BETTER IN THE MORNING

22
Q

Type 2 — effects of exercise

A

Multisystemic benefits
Exercise (cardio/strength)
Muscle, brain, adipose tissue, pancreas, liver, blood

23
Q

Type 2 — FITT (cardio)

A

Aerobic (moderate)
60-90% of max HR
20-60min/week
3-5x a week (daily if taking insulin therapy)
BETTER IN THE EVENING

24
Q

FITT (all diabetes)

A

F = min 2x/week (optimal 3-4)
I = light to moderate (60-75% 1RM)
T = 6-10 exercises, 10-15 reps, 2-3 sets
- More endurance
- Strength would be <6 reps
T = major muscle groups (lower body + core for balance)

25
Diabetes + stress
Stress increases blood glucose levels Due to cortisol Chronic high levels = increased insulin resistance
26
Diabetes + smoking
High glucose levels + chemicals => attack blood vessels - Atherosclerosis + neuropathy Nicotine raises HbA1c => hyperglycemia => insulin resistance Raise in other protein complex → blockages in circulation
27
T2D prevention
(be more specific with the specifics, how + effect) Weight loss (correlation NOT causation) Rich diet (whole grain, fiber, good fat, etc) Smoking Physical activity LIFESTYLE
28
T2D treatment
Regulate blood sugar levels Lose weight (if overweight) Surgery Medication (stimulates the release of insulin, inhibits glucose release, improves insulin sensitivity)