4- Action Potentials and Synapses Flashcards
Intercellular transmission is
Chemical
Resting membrane potential
Negative
Action potential
Wave of transient depolarisation that travels down the axon
Action potential only occurs if
Threshold membrane potential is achieved
Absolute refractory period
All sodium channels inactivated
Enforces one way transmission
Relative refractory period
Some sodium channels inactivated
What does Propagate mean
Transmit
Saltatory conduction
Action potentials travelling from one node of ranvier to the next
Why are myelinated axons more effective
Fewer ions flow
Less ATP needed to pump them back
Temporal summation
Lots of excitatory post synaptic potentials summate over time to reach threshold
Spatial summation
Lots of synapses active at the same time- excitatory post synaptic transmissions summate to reach threshold
What is the main inhibitory neurotransmitter in the brain
GABA
What does GABA do
Opens chloride channels
This allows negative charge
Generates an inhibitory post synaptic potential
This makes it harder to depolarise the membrane
Harder for threshold to be reached so action potential is less likely