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CYP 450 > 3A4/5 > Flashcards

3A4/5 Flashcards

1
Q

Apalutamide

A

Strong inducer, Substrate

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2
Q

Aprepitant

A

Inducer, Moderate inhibitor, Substrate

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3
Q

Armodafinil

A

Inducer

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4
Q

Bosentan

A

Moderate inducer, Substrate

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5
Q

Brigatinib

A

Inducer, Substrate

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6
Q

Carbamazepine

A

Strong inducer, Substrate

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7
Q

Corticosteroids

A

Inducer

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8
Q

Dabrafenib

A

Inducer, Substrate

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9
Q

Efavirenz

A

Moderate inducer

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10
Q

Encorafenib

A

Strong inducer

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11
Q

Enzalutamide

A

Strong inducer, Substrate

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12
Q

Etravirine

A

Moderate inducer, Substrate

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13
Q

Lorlatinib

A

Moderate inducer, Substrate

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14
Q

Lumacaftor

A

Moderate inducer

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15
Q

Modafinil

A

Moderate inducer

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16
Q

Nevirapine

A

Inducer, Substrate

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17
Q

Phenobarbital

A

Inducer

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18
Q

Phenytoin

A

Strong inducer

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19
Q

Rifabutin

A

Inducer, Substrate

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20
Q

Rifampicin

A

Strong inducer

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21
Q

Ritonivir

A

Inducer, Strong inhibitor, Substrate

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22
Q

Rufinamide

A

inducer

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23
Q

St John’s wort

A

strong inducer

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24
Q

Vemurafenib

A

inducer, Substrate

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25
Q

Amiodarone

A

Inhibitor, Substrate

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26
Q

Asciminib

A

Inhibitor, Substrate

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27
Q

Atazanavir

A

Moderate inhibitor, Substrate

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28
Q

Avacopan

A

Inhibitor, Substrate

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29
Q

Ceritinib

A

Strong inhibitor, Substrate

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30
Q

Ciclosporin

A

Moderate inhibitor, Substrate

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31
Q

Clarithromycin

A

Strong inhibitor, Substrate

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32
Q

Cobicistat

A

Strong inhibitor, Substrate

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33
Q

Crizotinib

A

Moderate inhibitor, Substrate

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34
Q

Darunavir

A

Inhibitor, Substrate

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35
Q

Diltiazem

A

Moderate inhibitor, Substrate

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36
Q

Encorafenib

A

Inhibitor, Substrate

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37
Q

Erythromycin

A

Moderate inhibitor, Substrate

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38
Q

Fluconazole

A

Moderate inhibitor

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39
Q

Fluvoxamine

A

Moderate inhibitor

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40
Q

Grapefruit juice

A

Moderate inhibitor

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41
Q

Idelalisib

A

Strong inhibitor, Substrate

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42
Q

Imatinib

A

Moderate inhibitor, Substrate

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43
Q

Isavucinazole

A

Moderate inhibitor, Substrate

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44
Q

Itraconazole

A

Strong inhibitor, Substrate

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45
Q

Ketoconazole

A

Strong inhibitor, Substrate

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46
Q

Larotrectinib

A

Inhibitor, Substrate

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47
Q

Lenacapavir

A

Moderate inhibitor, Substrate

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48
Q

Letermovir

A

Moderate inhibitor

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49
Q

Lopinavir

A

Inhibitor, Substrate

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50
Q

Maribavir

A

Inhibitor, Substrate

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51
Q

Miconazole

A

Inhibitor

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52
Q

Netupitant

A

Inhibitor, Substrate

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53
Q

Palbociclib

A

Inhibitor, Substrate

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54
Q

Posaconazole

A

Strong inhibitor

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55
Q

Ribociclib

A

Inhibitor, Substrate

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56
Q

Stiripentol

A

Inhibitor, Substrate

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57
Q

Ticagrelor

A

Inhibitor, Substrate

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58
Q

Verapamil

A

Moderate inhibitor, Substrate

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59
Q

Voriconazole

A

Strong inhibitor, Substrate

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60
Q

Abemaciclib

A

Substrate

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61
Q

Abiraterone

A

Substrate

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62
Q

Acalabrutinib

A

Substrate

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63
Q

Alfentanil

A

Substrate

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64
Q

Alprazolam

A

Substrate

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65
Q

Amitriptyline

A

Substrate

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66
Q

Apixaban

A

Substrate

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67
Q

Apremilast

A

Substrate

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68
Q

Aripiprazole

A

Substrate

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69
Q

Atorvastatin

A

Substrate

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70
Q

Avacopan

A

Substrate

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71
Q

Avanafil

A

Substrate

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72
Q

Avatrombopag

A

Substrate

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73
Q

Axitinib

A

Substrate

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74
Q

Betamethasone

A

Substrate

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75
Q

Bictegravir

A

Substrate

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76
Q

Bortezomib

A

Substrate

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77
Q

Brentuximab vedotin

A

Substrate

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78
Q

Brexpiprazole

A

Substrate

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79
Q

Buspirone

A

Substrate

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80
Q

Budesonide

A

Substrate

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81
Q

Busulfan

A

Substrate

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82
Q

Cabazitaxel

A

Substrate

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83
Q

Cabozantinib

A

Substrate

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84
Q

Cannabidol

A

Substrate

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84
Q

Cariprazine

A

Substrate

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85
Q

Cinacalcet

86
Q

Cisapride

87
Q

Clopidogrel

88
Q

Cobimetinib

89
Q

Cocaine

90
Q

Codeine

91
Q

Colchicine

92
Q

Cyclophosphamide

93
Q

Dapoxetine

94
Q

Darifenacin

95
Q

Darolutamide

96
Q

Dasatinib

97
Q

Dexamethasone

98
Q

Diazepam

99
Q

Disopyramide

100
Q

Docetaxel

101
Q

Domperidone

102
Q

Donepezil

103
Q

Eletriptan

104
Q

Elexacaftor

105
Q

Elvitegravir

106
Q

Enfortumab vedotin

107
Q

Entrectinib

108
Q

Eplerenone

109
Q

Ergometrine

110
Q

Erlotinib

111
Q

Esomeprazole

112
Q

Ethinylestradiol

113
Q

Etonogestrel

114
Q

Etoposide

115
Q

Etoricoxib

116
Q

Everolimuse

117
Q

Felodipine

118
Q

Fentanyl

119
Q

Finerenone

120
Q

Fluticasone

121
Q

Fluvastatin

122
Q

Fostemsavir

123
Q

Galantamine

124
Q

Gefitinib

125
Q

Filteritinib

126
Q

Guanfacine

127
Q

Haloperidol

128
Q

Hydrocortisone

129
Q

Ibrutinib

130
Q

Ifosfamide

131
Q

Imipramine

132
Q

Irinotecan

133
Q

Ivabradine

134
Q

Ivacaftor

135
Q

Lapatinib

136
Q

Lemborexant

137
Q

Lercanidipine

138
Q

Levonorgestrel

139
Q

Lidocaine

140
Q

Lurasidone

141
Q

Macitentan

142
Q

Maraviroc

143
Q

Mavacamten

144
Q

Methylprednisolone

145
Q

Midazolam

146
Q

Midostaurin

147
Q

Mifepristone

148
Q

Mirabegron

149
Q

Mirtazipine

150
Q

Nifedipine

151
Q

Nilotinib

152
Q

Nimodipine

153
Q

Nirmatrelvir

154
Q

Norethisterone

155
Q

Olaparib

156
Q

Omeprazole

157
Q

Ondansetron

158
Q

Osimertinib

159
Q

Oxycodone

160
Q

Paclitaxel

161
Q

Perampanel

162
Q

Pazopanib

163
Q

Pomalidomide

164
Q

Ponatinib

165
Q

Propranolol

166
Q

Quetiapine

167
Q

Quinine

168
Q

Reboxetine

169
Q

Regorafenib

170
Q

Rilpivirine

171
Q

Ripretinib

172
Q

Risperidone

173
Q

Rivaroxaban

174
Q

Romidepsin

175
Q

Ruxolitinib

176
Q

Salmeterol

177
Q

Sildenafil

178
Q

Silodosin

179
Q

Simvastatin

180
Q

Siponimod

181
Q

Sirolimus

182
Q

Solifenacin

183
Q

Sonidegib

184
Q

Sorafenib

185
Q

Sunitinib

186
Q

Suvorexant

187
Q

Tacrolimus

188
Q

Tadalafil

189
Q

Tamoxifen

190
Q

Tezacaftor

191
Q

Tiagabine

192
Q

Tofacitinib

193
Q

Tolterodine

194
Q

Tolvaptan

195
Q

Toremifene

196
Q

Trabectedin

197
Q

Tramadol

198
Q

Triamcinolone

199
Q

Ulipristal

200
Q

Upadacitinib

201
Q

Vandetanib

202
Q

Velpatasvir

203
Q

Venetoclax

204
Q

Venlafaxine

205
Q

Vinblastine

206
Q

Vincristine

207
Q

Vinorelbine

208
Q

Voxilaprevir

209
Q

Warfain (R-isomer)

210
Q

Zanubrutinib

211
Q

Ziprasidone

212
Q

Zolpdem

CYP 450 (8 decks)

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