3.8 The cell cycle Flashcards
When is the cell cycle implimented?
cells that do not divide continuously undergo a regular cell division separated by periods of growth.
What are the 3 stages of the cell cycle and what do they involve?
1) INTERPHASE: no division takes place (resting phase) takes up 90% of the cycle.
2) NUCLEAR DIVISION: when the nucleus divides either into 2 (mitosis) or 4 (meiosis)
3) CYTOKINESIS: division of the cytoplasm to create new cells
What is cancer?
- the uncontrolled growth and division of cells caused by damage to the genes that regulate mitosis and the cell cycle.
- this causes a group of abnormal cells to develop and constantly expand. only malignant tumors are cancerous.
Why do cells divide by mitosis?
- either to increase the size of a tissue during development (growth) or to replace dead or worn out cells (repair)
- mitosis is controlled by 2 genes, and a mutation to either of these can result in uncontrolled mitosis.
What is the difference between benign and malignant tumours?
- malignant tumours grow rapidly, are less compact, and can be lethal
- benign tumours grow slowly, are compact and not lethal
how do cancer treatments work?
by blocking a part of the cell cycle and killing dividing cells so that the tumour growth ceases.
How do drugs disrupt the cell cycle?
- prevents DNA from replicating
- inhibiting the metaphase by interfering with spindle fibre formation