3.8 The cell cycle Flashcards

1
Q

When is the cell cycle implimented?

A

cells that do not divide continuously undergo a regular cell division separated by periods of growth.

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2
Q

What are the 3 stages of the cell cycle and what do they involve?

A

1) INTERPHASE: no division takes place (resting phase) takes up 90% of the cycle.
2) NUCLEAR DIVISION: when the nucleus divides either into 2 (mitosis) or 4 (meiosis)
3) CYTOKINESIS: division of the cytoplasm to create new cells

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3
Q

What is cancer?

A
  • the uncontrolled growth and division of cells caused by damage to the genes that regulate mitosis and the cell cycle.
  • this causes a group of abnormal cells to develop and constantly expand. only malignant tumors are cancerous.
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4
Q

Why do cells divide by mitosis?

A
  • either to increase the size of a tissue during development (growth) or to replace dead or worn out cells (repair)
  • mitosis is controlled by 2 genes, and a mutation to either of these can result in uncontrolled mitosis.
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5
Q

What is the difference between benign and malignant tumours?

A
  • malignant tumours grow rapidly, are less compact, and can be lethal
  • benign tumours grow slowly, are compact and not lethal
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6
Q

how do cancer treatments work?

A

by blocking a part of the cell cycle and killing dividing cells so that the tumour growth ceases.

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7
Q

How do drugs disrupt the cell cycle?

A
  • prevents DNA from replicating

- inhibiting the metaphase by interfering with spindle fibre formation

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