3.3.2. Autonomics Flashcards
Name the andrenergic receptor that increases heart contractility, automaticity, and conduction velocity
Beta 1
Name the andrenergic receptor that increases arteriolar constriction and venoconstriction
Alpha 1
Name the andrenergic receptor(s) that increases arterioloar dilation and venodilation
Beta 2 for arteriolar dilation in skeletal muscle and liver. D1 for arteriolar dilation in kidney and mesentary. Beta 2 for venodilation
Name the andrenergic receptor contributing to bronchiole dilation
Beta 2
Name the andrenergic receptor contributing to radial muscle contraction (mydriasis: pupil dilation)
Alpha 1
Name the andrenergic receptor contributing to decreased GI tract and urinary bladder motility
Beta 2
Name the andrenergic receptor contributing to GI tract and bladder sphincter contraction
Alpha 1
Name the andrenergic receptor contributing to uterine relaxation
Beta 2
Name the andrenergic receptor contributing to liver gluconeogenesis, glycogenolysis (increased glucose level in the blood)
Alpha 1 and Beta 2
Name the andrenergic receptor contributing to increased lipolysis of adipose tissue (increased FA in blood)
Beta 1 and Beta 3
Name the andrenergic receptor contributing to decreased insulin secretion
Alpha 2 (this is a sympathetic response to allow more glucose for the brain and skeletal muscle)
Name the andrenergic receptor contributing to renin secretion
Beta 1
List the effects of low dose epinephrine on HR, BP, and TPR
- HR increases due to b1 activation
- BP systolic increases due to increased HR. Diastolic decreases due to decreased TPR
- TPR decreases. b2 has more of an effect than a1 at low dose, so vasodilation occurs and TPR decreases. The reverse effect occurs at high dose.
* Recall, epi activates a1, a2, b1, b2, b3
List the effects of norepinephrine on HR, BP, and TPR
- HR initially increases due to b1, but quickly decreases due to vagal response of M2.
- BP systolic increases due to b1. Diastolic increases due to a1.
- TPR inreases due to a1.
* Recall, norepi activates a1, a2, b1
List effects of dopamine on HR, BP, and TPR
- HR increases slightly due to b1
- systolic BP increases due to b1. Diastolic BP decreases due to d1 lowering TPR (D1>a1)
- TPR dereases due to D1 > a1
* Recall, DA activates (D1, b1>a1)