3.3 - How development is controlled Flashcards
What is meant by gene expression?
whether genes are switched on or off
Before transcription can begin, what stimulates the gene?
transcriptional factors
How does a transcriptional factor stimulate the gene?
forms a pre-initation complex with RNA polymerase
Which molecules switch off the transcriptional factors?
repressor molecules
How do repressor molecules switch off transcriptional factors?
repressors bind to transcriptional factors, preventing it from attaching to DNA.
without the transcriptional factor, the DNA cannot be transcribed
How does DNA methylation influence which genes are transcribed?
methyl groups attach to DNA which stops RNA polymerase binding and thus prevents transcription to mRNA