33. Anemia

Question 1

Ferrous Sulfate

Answer 1

FeroSul, Fer-In-Sol
20%

325 mg give 65 mg elemental iron

Question 2

Ferrous sulfate (dried)

Answer 2

Slow Fe

30%

Question 3

Ferrous fumarate

Answer 3

Ferretts, Ferrimin 150, Hemocyte

33%

Question 4

Ferrous gluconate

Answer 4

Ferate

12%

Question 5

Carbonyl Iron

Answer 5

FerraPlus 90, Ferralet 90

100%

Question 6

Polysaccharide Iron complex

Answer 6

Ferrex

100%

Question 7

Iron Dextran

Answer 7

InFeD

• High risk of anaphylactic reaction
• Required test dose

Question 8

Ferumoxytol

Answer 8

Feraheme

• High risk of anaphylactic reaction

Question 9

Cyanocobalamin

Answer 9

Vit B12 (Physicians EZ, oral generic or Nascobal)
Injection or nasal solution (Nascobal)

Question 10

Folic Acid

Folate

Answer 10

FA-8

0.4 mg - 1 mg

Question 11

Iron Requirement for Anemia

Answer 11

100 - 200 mg elemental iron / day

Question 12

Vitamin B12

Answer 12

IM/SC: 100 - 1,000 mcg /daily/weekly/monthly
Oral: 1,000 - 2,000 mcg daily
Nascobal: 500 mcg in on nostril once weekly

Question 13

Epoetin alfa

Answer 13

Procrit, Epogen
IV, SC
3x/week

Question 14

Darbapoetin alfa

Answer 14

Aranesp
IV, SC weekly

• t 1/2: 3 x longer

Question 15

Anti-dote of iron OD

Answer 15

Deferoxamine (Desferal)

Question 16

Deferoxamine

Answer 16

Desferal

Question 17

Acquired hemolytic anemia (drug-induced)

Answer 17

• Identify by positive Coombs test

- Stop offending agents

Question 18

Drug-induced Hemolytic Anemia Agents

Answer 18

1. ABX
   - PCN (piperacillin)
   - cephalosporins (ceftriaxone and cefotetan)
   - beta-lactamase inhibitors
   - rifampin, isoniazid
   - Nitrofurantoin
   - Sulfamethoxazoles
2. Ribavirin
3. Quinidine, quinine
4. Platinum-based chemo

Question 19

High risk agents with G-6PD Deficiency

Answer 19

1. ABX
   - Dapsone
   - Nitrofurantoin
   - Sulfamethoxazoles
2. Anti-parasite
   - Quinine, chloroquine, primaquine
3. Gout meds
   - Probenecid, rasburicase

Question 20

Iron sucrose

Answer 20

Venofer