🩷 3.1.5.1- Structure Of Dna And Rna Flashcards

1
Q

What does DNA stand for ?

A

Deoxyribonucleic acid

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2
Q

What does RNA stand for ?

A

Ribonucleic acid

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3
Q

What type of molecules are DNA and RNA ?

A

Information carrying molecules

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4
Q

In all living cells, what does DNA hold ?

A

Genetic information

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5
Q

What does RNA transfer genetic information from and to ?

A

From DNA to the ribosomes

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6
Q

What are ribosomes formed from?

A

RNA and proteins

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7
Q

What are both RNA and DNA polymers of ?

A

Nucleotides

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8
Q

What is each nucleotide formed from ?

A

A pentose, a nitrogen containing organic base and a phosphate group

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9
Q

What is the phosphate called in DNA ?

A

Deoxyribose

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10
Q

What are the possible nitrogen containing organic bases in DNA?

A

Adenine and thymine or cytosine and guanine

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11
Q

What is the phosphate in RNA called ?

A

Ribose

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12
Q

What are the possible nitrogen containing organic bases in RNA?

A

Adenine and uracil or cytosine and guanine

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13
Q

What type of bond is formed when a condensation reaction occurs between 2 nucleotides ?

A

A phosphodiester bond is formed

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14
Q

What are the polymers of nucleotides?

A

Nucleic acid

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15
Q

Compare dna and rna

A

Both dna and rna are polynucleotide chains
DNA is longer than rna
DNA is double stranded whereas rna is single stranded

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16
Q

What are DNA double strands referred to as being and what does this mean?

A

They are referred to as being anti parallel. This means one strand is inverted when compared to the other.

17
Q

What bond holds two DNA strands together ?

A

Hydrogen bonds

18
Q

Why is DNA very stable ?

A

Due to the many hydrogen and phosphodiester bonds

19
Q

DNA strands are held together by hydrogen bonds, why does this help it functionally?

A

This helps the DNA molecule as it can be easily unzipped in DNA replication and protein synthesis

20
Q

DNA is a large molecule which is coiled up, why is this a good functionally ?

A

It is good for storage i.e. lots of information can be stored in a relatively small space.

21
Q

What are the base pairs which code for proteins protected by ?

A

The sugar phosphate backbone

22
Q

What does the sequence of the base pairings determine ?

A

The structure of proteins, including enzymes

23
Q

Give the 5 steps of DNA semi conservative replication

A

1- DNA helically breaks the hydrogen bonds and the two strands unwind
2- Free floating DNA nucleotides line up by the complementary base pairings. This happens opposite both parent strands.
3- DNA polymerase joins adjacent nucleotides via phosphodiester bonds to form two new strands
4- Hydrogen bonds form between the bases of the new strand and the original strand and the helix reforms
5- There is now an identical copy of the DNA in two new cells. One strand in the original parent strand and the other in the newly formed strand. Hence semi conservative replication.

24
Q

What end of the nucleotides is dna polymerase complementary to?

A

DNA polymerase is complementary to the 3’ (prime) end of the 3’ nucleotides

25
What direction does a DNA strands grow in ?
It grows in a 5’ to 3’ direction
26
What direction does the template strand then move in and why ?
It moves in a 3’ to 5’ direction as the strands are anti parallel hence inverted
27
Who formed the model of DNA ?
Watson and crick
28
Who carried out the DNA experiment evidence for DNA semi conservative replication ?
Meselsen and Stahl
29
What was the simplified method for meselsons experiment ?
1- Grow bacteria in nitrogen 15 2- Transfer cells to nitrogen 14 for one generation 3- Grow for second generation in nitrogen 14