3.1.2i) The role of haemoglobin in transporting oxygen and carbon dioxide Flashcards
Erythrocytes specialised features
Biconcave shape
Large SA - increasing SA available for diffusion of gases
Small size - to pass through narrow capillaries
Continuously made in the red bone marrow in adults
When mature erythrocytes enter the circulation they have lost their nuclei - maximises the amount of so they only last for about 120 days in the bloodstream
Haemoglobin
A very large globular conjugated protein
4 peptide chains with an iron containing haem prosthetic group
300 million haemoglobin molecules in each red blood cell & each haemoglobin molecules in each red blood cell & each haemoglobin molecule can bind to 4 oxygen molecules
Oxyhaemoglobin
Oxygen binding loosely to the haemoglobin
reversible reaction
Hb + 4O₂ ⇌ Hb(O₂)4