31. Sepsis 2 Flashcards
What are the treatments for sepsis
Antibiotics
Oran support
SEPSIS 6
What are the new therapies for sepss
Eritoran
Thrombomodulinm
Thymosin alpha 1/ ulinastatin
Melatonin
What is eritoran?
Block lipopolysacharide, competitive inhibitor
Studies have found its shite
Discuss Thrombomodulin
Limits thrombin generation, tires to activate protein C
Attempted to prevent DIC
Studies werent good enough?
How do thymosin alpha 1 and ulnistatin act in the treatment of sepsis
Induces T cells and reduces serine protease
Only sucessful in pre-clinical studies
Meta-analysis shows it was a beneficial treatment
“all trials conducted in china so its shite”- professor
Quadrauple blind study
Why can melatonin be used as a treatment for sepsis?
Antioxidant
Ampiphillic (gets everywhere)
Anti-inflammatory effect
Why can melatonin be used as a treatment for sepsis?
Antioxidant
Ampiphillic (gets everywhere)
Anti-inflammatory effect
