3.1 Development of reproductive tract

Question 1

how do the primitive sex cords form?

Answer 1

epithelium of genital ridges proliferates and penetrates intermediate mesoderm

Question 2

what is the testis determining factor

Answer 2

SRY gene

Question 3

what is the mesonephrenic duct converted into?

Answer 3

-vas deferens
-epididymis
-seminal vesicles
-ejaculatory duct

Question 4

what is the paramesonephrenic duct converted into?

Answer 4

-uterus
-fallopian tubes
-cervix
-upper 1/3 of vagina

Question 5

what could improper fusing of paramesonephrenic duct cause?

Answer 5

bicornuate uterus

Question 6

name 4 disorders of sexual development

Answer 6

1. turners syndrome
2. klinefelters syndrome
3. androgen insensitivity syndrome
   4.congenital adrenal hyperplasia

Question 7

describe turner’s syndrome

Answer 7

-genotype X0
-female internal and external genitalia
-ovaries degenerate in childhood
-delayed puberty
-coarctation of aorta
-short

Question 8

describe klinefelters syndrome

Answer 8

-genotype XXY
-male internal and external genitalia
-hypogonadism
-delayed puberty
-decreased body and facial hair

Question 9

describe congenital adrenal hyperplasia

Answer 9

-genotype XX
-excessive androgen exposure
-female internal genitalia (no MIH, mullein duct remains), male/ambiguous external

Question 10

describe androgen insensitivity syndrome

Answer 10

-genotype XY male
-phenotypically female
-male internal genitalia (Y, MIH)
-female external genitalia (faulty androgen receptor)