31: CRPS - Feilmeier Flashcards

1
Q

define complex regional pain syndrome

A

poorly understood “chronic inflammatory neuropathic” pain disorder characterized by pain out of proportion of injury and sensory changes

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2
Q

what are the potential causes of CRPS?

A
  • usually occurs after trauma - minor or major

- may have no traumatic, or very minor inciting event (10%)

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3
Q

hyperalgesia

A

shift in stimulus response to lower pain threshold or increase pain to above pain threshold stimuli

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4
Q

allodynia

A

pain from non-noxious stimulus on normal skin

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5
Q

sudomotor

A

edema or sweating abnormalities

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6
Q

trophic changes with CRPS

A
  • Hair and nail growth decreases
  • Skin thins
  • Fat atrophy
  • Adhesions and contractions of tendon and ligaments
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7
Q

end stage CRPS

A
  • decreased ROM
  • atrophy
  • weakness
  • and associated skin changes
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8
Q

theories for pathophys of CRPS

A
  • over activity of sympathetic nervous system (may be a coupling of myelinated A fibers and unmyelentated C fibers to sympathetic nerves)
  • peripheral response to nerve injury (normally midportion of nerve can’t create nerve pulses)
  • central sensitization (neurons of dorsal horn become sensitized to excess c-nociceptor input)
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9
Q
  • May develop after trauma without definable nerve damage (ex: ankle sprain)
  • Most common form
  • This is where “reflex sympathetic dystrophy” falls
A

CRPS I

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10
Q
  • Or “Causalgia”
  • Has the same clinical presentation but there is an identifiable nerve injury
  • Nerve injury not complete
A

CRPS II

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11
Q

synonyms for CRPS

A
  • Reflex sympathetic dystrophy
  • Causalgia
  • Sudeck’s atrophy
  • Sympathetically maintained pain
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12
Q

general definition of CRPS

A

CRSP describes an array of painful conditions that are characterized by a continuing (spontaneous and/or evoked) regional pain that is seemingly disproportionate in time or degree to the usual course of any known trauma or other lesion. The pain is regional (not in a specific nerve territory or dermatome) and usually has a distal predominance of abnormal sensory, motor, sudomotor, vasomotor, and/or trophic findings. The syndrome shows variable progression over time

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13
Q

Diagnostic criteria for CRPS

A
  1. Continuing pain, which is disproportionate to any inciting event
    - Must report at least one symptom in three of the four following categories (sensory, vasomotor, sudomotor/edema, motor/trophic)
    - must display at least one sign at time of evaluation in two or mor of the following categories (sensory, vasomotor, sudomotor/edema, motor/trophic)
    - there is no other better diagnosis
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14
Q

risk factors for CRPS

A
  • female
  • smokers
  • anxiety/depression
  • migraines
  • osteoporosis
  • preexisting neuropathy
  • asthma
  • recent menstrual disorders
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15
Q

describe the pain of CRPS

A
  • out of proportion
  • allodynia and hyperesthesia
  • doesn’t follow dermatome and can spread beyond area of injury
  • describe as severe and burning, throbbing or aching
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16
Q

sympathetic changes with CRPS “american flag leg”

A
  • Skin can be red, hot, dry and edematous

- May also become cold, blue, with mottling (livedo reticularus), and hyperhydrosis

17
Q

dystonia

A

severe muscle spasms that can cause severe deformity and joint dislocation

18
Q

Clinical staging of CRPS

A

Stage I – Acute

      • Skin warm, red and dry then may become blue and cold
      • May have hyperhydrosis
      • Edema
      • Severe pain with allodynia and hyperalgesia

Stage II - Dystrophic

      • Pain becomes more severe and diffuse
      • Edema becomes more hardened and limb can appear brawny
      • Hair and nail changes
      • X-ray changes
      • Muscle wasting begins

Stage III – Atrophic

      • Pain may start decreasing but motor and trophic changes increase
      • Tissue wasting occurs and can become permanent
19
Q

radiographic findings sudeck’s atrophy

A
  • Patchy osteoporosis
  • Accentuated joints
  • Subchondral bone resorption
  • Ground-glass appearance
20
Q

what would a bone scan show for CRPS?

A
  • Three phase technesium 99 bone scan
  • Noted increased periarticular uptake, particularly in 3rd phase
  • Sensitivity and specificity reported 50-80%
  • Sensitivity decrease and specificity increases with disease duration
21
Q

who do you refer a possible CRPS pt to?

A

a neurologist, not a pain specialist, because they will do a work up, but then also the pain specialist because they will manage the chronic pain meds

22
Q

1st line treatment CRPS

A

physical therapy (steady progression of gentle weight bearing, gradual desensitization to increasing sensory stimuli, massage, continued active and passive ROM)

23
Q

usually 1st line, short term treatment

A

corticosteroids ( not for over 1 month )

- treats inflammation, decrease tissue edema, and therefor decrease pain

24
Q

treatment to reduce bone modeling

A

bisphosphanates

25
Q

strong evidence treatment modalities

A
  • physical therapy
  • bisphosphonates
  • repetitive transcranial magnetic stimulation
26
Q

things to do to decrease incidence of CRPS

A
  • give local anesthetic block pre-operatively
  • vitamin C post-operatively
  • early ROM
  • careful, meticulous surgical technique