Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

TB consensus > 3 microbiology > Flashcards

3 microbiology Flashcards

1
Q

mycobateria are aerobic, nonmotile, slightly curved or straight bacilli (True or False)

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

classification of mycobacteria

A 
a. Mycobacteria tuberculosis complex - cause TB in humans & other mammals
a1 M. tuberculosis
a2 M. bovis
a3 M. caprae
a4 M. africanum
a5 M. microti
a6 M. canetti
a7 M. pinnipedii

b. non-tuberculous mycobacteria
b1 M.avium intracellulare
b2 M.kansasii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What Mycobaterium is BCG derived

A

M.bovis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

primary MOT of M.bovis

A

ingestion of contaminated milk & meat

  • M.bovis requires oxygen for growth and is inhibited by higher tension required by M. tuberculosis
  • it is also intrinsically resistant to PYRAZINAMIDE
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

NTM that causes pulmonary disease

A

M. avium complex
M. kansasii
M. xenopi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

NTM that causes lymphadenitis particularly in children

A

M. avium

M. scrofulaceum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

NTM that causes disseminated disease among HIV patients

A

MAC

M. kanasii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

true or false: NTM are not transmissible from 1 human to another and are relatively drug resistant compared to M.tuberculosis

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what enhances growth rate of mycobacterium

A

6-8% carbon dioxide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

optimal temperature of growth of M.tuberculosis

A

35-40C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

responsible for the morphologic appearance of M. tuberculosis cells

A

cord factor

  • serpentine cords of bacilli in close, parallel arrangements
  • role in human TB is unknown
  • in mice its demonstrated as strong inducers of cytokine secretion as well as neutrophil recruitment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

peripherally located glycolipids that inhibit fusion of secondary lysosomes with bacilli containing phagosomes within a macrophage

A

Sulfatide

- possibly promoting intracellular survival of the organism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

important molecule in mycobacterial cell wall

A

Lipoarabinomannan (LAM)

- dominant mycobacterial antigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

variant of MTBC that is responsible for enhanced bacilli survival and entry into macrophages

A

Man-LAM (mannan-capped LAM)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

doubling time of TB bacilli

A

18-24hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

gold standard for diagnosis of TB

A

demonstration of organism by culture

17
Q

specimen for diagnosis

A 
pulmonary secretion
urine
genital discharge
CSF
blood
pleural fluid
other biologic fluid
18
Q

hot method

A

Ziehl-Neelsen

  • uses carbol fuchsin
  • red rods against blue background
19
Q

cold stain

A

Kinyoun

- uses higher concentration of phenol with carbol fuchsin

20
Q

uses auramine instead of carbol fuchsin

A

Auramine O stain

- fluorescing tb bacilli

21
Q

most popular egg based culture media

A

Lowenstein Jensen

TB consensus (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions