2 epidemiology

Question 1

TB is the 6th leading cause of morbidity and mortality in the Philippines (True or False)

Answer 1

TRUE

Question 2

most significant risk factor for the progression of dormant TB infection to clinical disease

Answer 2

HIV

Question 3

HIV positive individuals are 20-30x more likely to develop TB (True or False)

Answer 3

True

Question 4

leading cause of death in adults with HIV

Answer 4

TB

Question 5

MOT of M.tuberculosis

Answer 5

airborne particles as droplet nuclei measuring 1-5microns in diameter

Question 6

other MOT of M.tuberculosis

Answer 6

• ingestion of contaminated, unpasteurized dairy products from infected cattle resulting in bovine TB
• skin inoculation from contamination of an abrasion w/c usually occurs among pathologists and laboratory personnel (Prosecutor’s wart)

Question 7

age of children with increased risk for progression of TB disease and disseminated disease

Answer 7

< 5yo

Question 8

percentage of infected person who do not receive treatment for LTBI will develop TB disease

Answer 8

5-10%

Question 9

3-4% of infected individual progress to active TB during 1st year after infection

Answer 9

tuberculin conversion

Question 10

person high risk for developing TB disease

Answer 10

1. those who have been recently infected w/ TB bacteria

2. those who have medical condition that weaken the immune system

Question 11

person who have been recently infected with TB bacteria

Answer 11

• close contact of a person w/ infectious TB disease
• person who have migrated from areas of the world with high rates of TB
• children <5yo who have a (+) TST
• groups w/ high rates of TB transmission, such as homeless person, injection drug user, person w/ HIV

Question 12

person with medical condition that weaken the immune system

Answer 12

• babies and young child often have weak immune system
• HIV/AIDS
• substance abuse
• silicosis
• DM
• severe kidney disease
• undernutrition
• organ transplant
• malignancies
• immunosuppression