3: Membrane transport Flashcards
What are the two main factors determining whether or not a particle can cross the plasma membrane without assistance?
It’s lipid solubility (is it polar or nonpolar?)
Size of the particle
Does passive transport require energy?
No
Active transport requires energy. What is the energy derived from?
ATP
Name two types of unassisted passive transport which occur across the plasma membrane.
Diffusion
Movement along electrochemical gradient (i.e opposites attract)
Osmosis
According to Fick’s Law of Diffusion, what are some factors influencing diffusion across a plasma membrane?
1. Magnitude of concentration gradient
2. Surface area of membrane
3. Lipid solubility
4. Size of particle
5. Thickness of membrane
What do you get when you combine a concentration gradient (diffusion) with an electrical gradient (opposites attract)?
Electrochemical gradient
What is osmosis?
Diffusion of water down its concentration gradient through a selectively permeable membrane
What kind of plasma protein channel do water molecules pass through by osmosis?
Aquaporins
During osmosis, water moves from a ___ water concentration to a ___ water concentration.
higher
lower
During osmosis, water moves from a ___ solute concentration to a ___ solute concentration.
lower
higher
What is osmolarity?
The concentration of osmotically active particles in a solution
What is the unit of measurement for osmolarity?
Osmoles per litre (Osm/L)
What is tonicity?
The effect that a solution has on cell volume
Water moves from ___ osmolarity to ___ osmolarity.
low , high
How many sodium ions are transported by NaKATPase?
In which direction?
3
Out of the cell