3. Infection Flashcards

1
Q

With regard to osteomyelitis, radiographs will be normal for

A

7-10 days

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2
Q

Osteomyelitis spread in children and adults

A

Children have hematogenous spread usually hitting the long bones (metaphysis). Adults are more likely to have direct spread (in diabetic).

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3
Q

General rule in osteomyelitis

A

Septic joints more common in adults.

Osteomyelitis more common in kids.

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4
Q

Classic look of osteomyelitis

A

Hallmarks are destruction of bone and periosteal new bone formation.

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5
Q

Osteomyelitis in Spine =

A

IV drug user

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6
Q

Psoas Muscle Abscess =

A

TB

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7
Q

Unilateral SI joint =

A

IV drug user

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8
Q

Osteomyelitis in Spine with Kyphosis (Gibbus Deformity) =

A

TB

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9
Q

Sequestrum

A

Piece of necrotic bone surround by granulation tissue

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10
Q

Involucrum =

A

Thick sheath of periosteal bone around sequestrum

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11
Q

Cloaca =

A

Defect in the periosteum (bone skin) caused by infection

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12
Q

Sinus Tract

A

A channel from the bone to the skin (lined with granulation tissue).

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13
Q

Chronic Osteomyelitis:

A

This is defined as osteomyelitis lasting longer than 6 weeks.

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14
Q

Draining sinus tracts are a risk factor for

A

squamous cell CA

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15
Q

Most specific sign of active chronic osteomyelitis

A

presence of a sequestrum (best shown with computed tomography)

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16
Q

MRl diagnosis of healed osteomyelitis is based on =

A

Return of normal fatty marrow

17
Q

Acute Bacterial Osteomyelitis

A

3 categories

1) hematogenous seeding {most common in child)

2) contiguous spread

3) direct inoculation of the bone either from surgery or trauma.

18
Q

Acute hematogenous osteomyelitis has a predilection for the long bones of the body, specifically the

A

MEtaphysis

which has the best blood flow and allows for spreading of the infection via small channels in the bone that lead to the subperiosteal space

In the slightly older baby (<18 months) these vessels from the metaphysis to the epiphysis atrophy and the growth plate stops the spread (although spread can still occur). This creates a “septic tank” effect. This same thing happens with certain cancers (leukemia); the garbage gets stuck in the septic tank (metaphysis). Once the growth plates fuse, this obstruction is no longer present.

19
Q
A

Osteomyelitis

Low signal in the bone marrow on T1 imaging adjacent to an ulcer or cellulitis is diagnostic.

20
Q

The Ghost Sign: Neuropathic Bone vs
Osteomyelitis in a Neuropathic Bone

A

A bone that becomes a ghost (poor definition of margins) on T1 imaging, but then re-appears (more morphologically distinct) on T2, or after giving IV contrast, is more likely to have osteomyelitis.

21
Q

Discitis / Osteomyelitis mechanism

A

Infection of the disc and infection of the vertebral body nearly always go together.

The reason has to do with the route of seeding;

22
Q
A

Typical Look of Discitis / Osteomyelitis

23
Q
A

Epidural Abscess

This is an infected collection between the dura and periosteum.

24
Q

Discitis / Osteomyelitis Trivia

A

Adults: Surger, procedue, systemic infection
Children: <5 = hematogeneous spread
Most common bug: Staph A - IV drug
Almost always ESR and CRP are elevated

25
Q

Pediatric Discitis I Osteomyelitis

A

Children have direct blood supply to the intervertebral disc, so they can get isolated discitis.

Isolated Discitis is basically never seen in adults

26
Q

Kid (< 4y.o.) + URTI + back pain =

A

Think of Pediatric discitis

27
Q

Pott Disease

A

“spare the disc space”
have multi-level thoracic “skip ’ involvement

Buzzwords:
“Large paraspinal abscess”
“Calcified Psoas Abscess ”
“Gibbus Deformity ”

28
Q

‘‘Gibbus Deformity”

A
29
Q
A

TB spondylodiscitis

30
Q

DDxfor Pott’s Disease

A
31
Q

What can also have disc space preservation?

A

Brucellosis

32
Q
A

“‘Tuberculosis Dactylitis” (Spina Ventosa)

Kids + Short tubular bones of the hands and fit

diaphyseal expansile lesion with soft tissue swelling.

33
Q
A

‘‘Rice Bodies”

These are sloughed, infarcted synovium seen with end stage RA, and TB infection ofjoints

34
Q

Septic Arthritis

A

You see this the most in large joints which have an abundant blood supply to the metaphysis (shoulder, hip, knee).

IV drug users will get it in the SIjoint, and sternoclavicularjoint.

35
Q
A

Septic Arthritis

Loss of joint space + Destriction + osteopenia

36
Q

Pneumoarthrogram Sign

A

If you can demonstrate air within a joint you can exclude a joint effusion.

No joint effusion = No septic joint

37
Q

Necrotizing Fasciitis

A

Very bad = kills very quickly = rare

Hx = HIV, Transplan, DM, alcoholics

From Group A strep

GAS in soft tissues

38
Q

Necrotizing Fasciitis in Scrotum =

A

Fournier Gangrene