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3 - Energy Transformation & Metabolism Flashcards

1
Q

Laws of Thermodynamics

A

Principles that govern energy exchange, including heat exchange and the performance of work.

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2
Q

Energy Transfer

A

Movement of ATP from one compound to another so it can be used.

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3
Q

Hepatocyte

A

Liver Cell

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4
Q

Myocyte

A

Muscle Cell

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5
Q

Adipocyte

A

Fat Cell

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6
Q

ATP/PCr System

A

Composed of ATP and phophocreatine, this system replenishes oxygen rapidly without the use of oxygen.

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7
Q

Creatine Kinase

A

Isoenzyme found in muscle and brain tissue that catalyzes the formation of ATP; higher after tissue injury.

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8
Q

Creatine

A

Nitrogenous substance, derived from arginine, glycine and methionine, found in muscle tissue.

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9
Q

Phosphocreatine (PCR)

A

Compound of creatine (Cr) and phosphoric acid (P) found in muscle.

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10
Q

Glycolytic System

A

Process of breaking down glucose for energy; can be fast or slow.

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11
Q

Pyruvate

A

Salt of pyruvic acid; the end product of glycolysis.

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12
Q

NADH

A

Reduced form of NAD; used to transfer electrons.

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13
Q

Hydrogen Ion

A

The cation of acids; consists of a hydrogen atom whose electron has been transferred to the anion of the acid.

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14
Q

NAD+

A

Co-enzyme of dehydrogenases; plays a role in intermediary metabolism as an oxidizing agent or reducing agent for metabolites.

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15
Q

Lactic Acid

A

An organic byproduct of anaerobic metabolism derived from pyruvic acid; can be used as an energy source for cells.

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16
Q

Oxidative Phosphorylation

A

The phosphorylation of ATP coupled to the electron transport system.

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17
Q

Muscle Acidity

A

An acidic environment created when the pH level of muscle cells falls below 7.

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18
Q

Krebs Cycle

A

A major metabolic pathway that involves a series of enzymatic reactions that convert pyruvic acid from food to acetyl-CoA for energy.

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19
Q

Electron Transport Chain

A

Set of compounds that transfers electrons to a donor that creates energy.

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20
Q

Acetyl-CoA

A

Co-enzyme that plays a role in intermediary metabolism; can enter the Krebs Cycle to produce energy and be used for fatty acid synthesis.

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21
Q

Beta Oxidation

A

Breakdown of fatty acids that takes place in the mitochondria and peroxisomes.

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22
Q

FAD+

A

Riboflavin-derived hydrogen acceptor in the Krebs cycle.

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23
Q

FADH2

A

The reduced form of FAD+

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24
Q

Cytochrome

A

Protein found in mitochondria (inner membrane) that transports electrons.

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25
Proton
Particle with a positive charge, usually regarded as a hydrogen ion; when the proton gradient shifts in the electron transport chain, energy conversion occurs.
26
Glycogenesis
Systhesis of glycogen.
27
Glucose 6-Phosphate
Phosphorylated form of glucose that won't diffuse out of a cell.
28
Glycogen Synthase
Enzyme necessary for the conversion of excess glucose into stored glycogen.
29
Epinephrine
Hormone and neurotransmitter; also known as adrenaline.
30
Norepinephrine
Hormone and nuerotransmitter; also known as noradrenaline.
31
Glycogen Phosphorylase
Enzyme necessary for glycogenolysis; breaks glycogen into glucose units.
32
Glycogenolysis
Breakdown of stored glycogen to glucose.
33
Glucagon
Hormone secreted by the pancreas to increase blood glucose levels.
34
a-cells
Endocrine cells of the pancreas that secrete glucagon.
35
Adrenal Medulla
Central part of the adrenal gland that secretes epinephrine, norepinephrine and dopamine.
36
Glycolysis
Series of reactions in the cytosol that converts glucose into pyruvic acid and ultimately ATP.
37
Anaerobic Threshold
The point at which lactic acid begins to accumulate in the bloodstream.
38
Oxaloacetate
Intermediate that couples with acetyl Co-A to form citrate.
39
Fat Adaptation
A higher capacity to oxidize fat.
40
Plasma
Liquid component of blood that suspends blood cells; contains water, glucose, proteins and hormones.
41
Gluconeogenesis
Conversion of non-carbohydrate compounds (i.e., amino acids, pyruvate, glycerol) to glucose.
42
Cori Cycle
Use of lactate produced in the muscles by the liver for the production of glucose.
43
Adipose Tissue
Fat Tissue
44
Lipolysis
Breakdown of triglycerides into fatty acids and glycerol.
45
Hormone Sensitive Lipase
Enzyme of the cytosol that frees fatty acids and glycerol.
46
Lipid Mobilization
Using lipids as a fuel source.
47
Growth Hormone
Anabolic hormone that causes growth and cell reproduction; also known as somatotropin.
48
Aerobic
With oxygen present.
49
Anaerobic
Without oxygen present.
50
Monoglyceride
A glycerol with one fatty acid chain.
51
Diglyceride
A glycerol with two fatty acid chains.
52
Fatty Acid Synthase Chain
System of enzymes involved in the synthesis of fatty acids.
53
Elongation
Addition of carbons on a fatty acid chain.
54
Saturated Fatty Acid
A fatty acid with no double bonds in the chain.
55
Desaturation
Removal of hydrogen atoms to form a double bond.
56
Monounsaturated Fatty Acid
A single double bond in the fatty acid chain.
57
Very Low Density Lipoprotein Particles
Particles used in lipid transport; assembled in the liver by cholesterol and apolipoproteins, converted to LDL.
58
Lipogenic Enzymes
Enzyme involved with the synthesis of fat.
59
Alpha Linolenic Acid (ALA)
Unsaturated omega-3 fatty acid, see linolenic acid.
60
Omega-3
Family of unsaturated fatty acids characterized by a carbon-carbon double bond three spaces in from the methyl end.
61
Linoleic Acid
Unsaturated omega-6 fatty acid considered essential to the human diet.
62
Omega-6
Family of unsaturated fatty acids characterized by a carbon-carbon double bond six spaces in from the methyl end.
63
Polyunsaturated Fatty Acid
A fatty acid with multiple double bonds in the chain.
64
Chylomicron
A lipoprotein that transports cholesterol and triglyceride from the small intestines to tissues of the body.
65
Lipoprotein
A class of proteins with hydrophobic core of triglycerides or cholesterol surrounded by hydrophilic phospholipids, apolipoproteins and cholesterol.
66
Cholesterol
Lipid/Sterol contained in body's cells and fluids that acts as a precursor to hormones and bodily structures.
67
Statin Drugs
Pharmaceutical agents that decrease cholesterol production within the body via downregulation of HMG-CoA reductase.
68
Apolipoprotein
Lipid binding protein that is part of a lipoprotein.
69
LDL Cholesterol
A lipoprotein that transports triglyceride and cholesterol from the liver to body tissues.
70
HDL Cholesterol
A lipoprotein that transports fatty acids and cholesterol from the body tissues to the liver.
71
Lecithin-Cholesterol Acyltransferase (LCAT)
An enzyme that is used to convert cholesterol to a transportable form for lipoproteins.
72
Atherosclerosis
Development of plaque in the lumen (interior space) of blood vessels.
73
Plasma Pool of Amino Acids
Reserve of amino acids found in blood plasma.
74
Non-Essential Amino Acids
Amino acid that does not need to be included in the diet.
75
Essential Amino Acid
Amino acid that must be included in the diet.
76
Peptide Chain
Short polymer formed from linking amino acids.
77
Deanimation
Removal of an anime group from a compound.
78
Branched Chain Amino Acid (BCAA)
Amino acid with aliphatic side chain that is non-linear.
79
Carbon Skeleton
Chain, branches or rings of carbon atoms that form organic molecules.
80
Amine
One of a group of organic nitrogen compounds.
81
Ammonia
Also known as NH3, a very basic end product of protein metabolism.
82
Urea Cycle
Cycle that takes place in the liver and creates urea from ammonia and carbon dioxide.
83
Urea
Water-soluble final nitrogenous excretion product synthesized from ammonia and carbon dioxide, found in urine.
84
a-Ketoacid
An organic acid containing a functional ketone group and a carboxylic acid.
85
Transamination
The transfer of an amino group from an amino acid to an alpha-keto acid.
86
Protein Turnover
Balance between protein synthesis and breakdown.
87
Protein Synthesis
(Re)Building of proteins.
88
Protein Breakdown
Degradation of proteins.

PN (5 decks)

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