[3] Chronic Obstructive Pulmonary Disease Flashcards
What is Third Hand Smoke?
Smoke clinging to materials (shirts)
Hallmark of COPD
Irreversible Progressive Airflow Limitation
What immunologic cells are usually found in Asthma?
Eosinophils
Mainstay Agent for Asthma
Inhaled Steroids
Mainstay Agent for COPD
Bronchodilators
Main Difference of COPD and Asthma
Chronic Airway Inflammation
What segments of the lung has the highest airflow limitation?
Segments 5th to 7th generation
How do you confirm COPD?
Symptoms
Spirometry
Age
Symptoms:
- Shortness of Breath
- Chronic Cough
- Sputum Production
Spirometry: Post Bronchodilator FEV1/FVC < 70%
40 years and above
Spirometry Cutoff for Asthma
> 0.75
Mild COPD FEV1 Value
> = 80%
Is an XRay useful for COPD?
No not really, but it can be useful for other disease
5A’s To Help Someone Quit Smoking
Ask Advise Assess Assist Arrange
Inheritance Pattern of Cystic Fibrosis
Autosomal Recessive Gene in CFTR
Gold Standard for Cystic Fibrosis Diagnosis
Gibson-Cooke Sweat Test
COPD is characterized by:
a. Persistent airflow limitation, progressive, not fully reversible
b. Persistent airflow limitation, non-inflammatory, fully irreversible
c. Persistent airflow limitation, acute, not fully reversible
d. Persistent airflow obstruction, chronic, reversible
A
Asthma and COPD are both characterized by ________ but differ from ________
a. Airflow limitation; main inflammatory cells involved
b. Airway hyper-responsiveness; airway inflammation
c. Irreversibility; extent of damage to lung parenchyma
d. Main types of inflammatory cells involved; area of lung affected
(c/o Mark Velasco)
A
Diagnosis of COPD is confirmed by ________ and a postbronchodilator FEV1/FVC value of ______ confirms the presence of airflow limitation that is not fully reversible
a. COPD Assessment Test (CAT); 50%
b. Arterial blood gas: 50%
c. Spirometry; 70%
d. mMRC Breathlessness Scale; 70%
(c/o Mark Velasco)
C
The following is true in management of COPD patients:
a. Regular physical activity should be encouraged in COPD patients
b. Some existing medications for COPD has already been shown to conclusively modify long-term decline in lung function
c. Influenza and pneumococcal vaccinations are absolutely contraindicated in COPD patients
d. COPD is not largely preventable and comorbidities should be managed differently
(c/o Mark Velasco)
A
True of Reed classification of bronchiecstasis:
a. The Reed classification is more radiological; it’s not that clinically important and does not affect management
b. Cylindrical bronchiecstasis: sections of bronchi are consistently widened
c. Varicose bronchiecstasis: local constrictions and irregular pattern that looks like varicose veins
d. Sacular bronchiecstasis: dilatation increases toward the periphery of lungs; bronchi terminates in cystic or balloon-like structures
e. All of the above
(c/o Mark Velasco)
E
True of medical and surgical management of bronchiecstasis EXCEPT:
a. LABA, ICS and nebulized antibiotics should be administered before physiotherapy when airways have more secretions
b. Postural drainage at least once a day and physical exertion aids in mucus clearance
c. Surgical resection is the only curative treatment
d. Lung transplantation is advised if respiratory failure occurs despite optimal medical treatment
(c/o Mark Velasco)
A