3- Abnormal Pregnancy III & IV Flashcards
Preterm labor is the most common cause of perinatal morbidity/ mortality, and can lead to long-term neuro impairment. How is preterm labor defined?
Regular contractions between 20 - 37 weeks resulting in cervical changes
Pt presents with menstrual-like cramps, low/ dull backache, abd/ pelvic pressure, abd cramping, vaginal discharge, and painless uterine contractions. What are you concerned for?
Preterm labor
What is included as part of preterm labor eval aside from digital cervical exam, UA C+S +/- NST?
R/o ROM
US for cervical length
GBS culture
What diagnostic test is used as a predictive value for preterm labor?
Fetal fibronectin (fFN) = “glue like” glycoprotein
Present @ term, but NOT @ 22-35 wks
(none = (-) predictive value, (+) = (+) predictive value)
What criteria must be met for a diagnosis of preterm labor?
Uterine contractions ≥ 4 q 20 min or ≥ 8 in 60 min PLUS
- cervical dilation ≥ 3cm or
- cervical length < 20mm on TVUS or
- cervical length 20-30mm on TVUS + (+) fFN
What is the management for preterm labor?
Hospitalize if < 34 weeks
+ betamethasone, tocolytic drugs, GBS abx, mg sulfate (neuroprotection)
What tocolytic agents are used in the management of preterm labor?
In-pt: Terbutaline, Mg Sulfate
Out-pt: Nifepidine, Indomethacin
What is defined as placental location close to or over the internal cervical os and is the leading cause of 3rd trimester bleeding?
Placenta previa
What is a specific RF for placenta previa?
Hx of prior c-section or uterine surgery
What are the 4 degrees of placenta previa?
Complete- internal os completely covered
Partial- internal os partially covered
Marginal- edge of placenta at margin of internal os
Low-lying- placenta < 2cm from internal os
Pt presents with mod-severe acute painless vaginal bleeding in the late 2nd or 3rd trimester. What are you concerned for?
Placenta previa
How is placenta previa diagnosed?
Start w/ transabdominal US
Confirm w/ TVUS
If placenta previa is detected in the 2nd trimester, what pt education can be provided?
Most resolve by 32-35 wks due to placental migration
(unless complete placenta previa)
What should you NEVER do on a known placenta previa pt?
Bimanual/ cervix exam
What is the management for placenta previa if presenting w/ spontaneous labor or hemorrhage?
Immediation c-section
What is the management for placenta previa if preterm w/o active bleeding?
Observe (home > hospital) until c-section @ 37-38 wks
Corticosteroids if < 37 wks, RhoGAM if Rh (-)
What complications are a/w placenta previa? (4)
Increased risk of:
- preterm delivery/ perinatal death
- placenta accreta (too deep/ firm into uterine wall)
- placenta increta (into uterine muscle)
- placenta percreta (through uterine muscle layers, most dangerous)
What is defined as abnormal premature separation of an otherwise normally implanted placenta that can cause 2nd/ 3rd trimester bleeding or hemorrhage?
Abruptio placentae
What are the types of placental abruption?
Marginal, partial, complete
(complete a/w increased risk of fetal death)
What is the greatest RF for placental abruption?
Abdominal trauma
(displaces uterus → detaches placenta)
What is the most common presentation of placental abruption?
Hemorrhage and abd pain
(others: fetal distress, rigid abd, irritable uterus, DIC)
What is included in the management of a placental abruption? (4)
Expectant if marginal
Tx shock/ stabilize hemodynamically
C-section if fetal distress
Corticosteroids if < 37 wks
What is defined as fetal blood vessels running unsupported through the membranes over the cervix and under the presenting fetal part and what is the problem w/ this condition?
Vasa previa
Membranes rupture → fetal blood supply vessels rupture → rapid fetal blood loss/ death
Multiple gestation pregnancies, 2nd trimester/ low-lying placentas, bi-lobed/ accessory lobed placentas, and IVF pregnancies are RF for what condition?
Vasa previa
Pt presents w/ vaginal bleeding w/ ROM and changes in fetal heart rate. What are you concerned for and what is used for confirmation of dx?
Vasa previa
Dx w/ color doppler US
What is the management for vasa previa?
Hospitalize if 3rd trimester
Corticosteroids b/w 28-32 wks
Pelvic rest
C-section @ 35 wks
How is premature rupture of membranes (PROM) defined?
Spontaneous rupture of membranes before the onset of labor
90% of women at term will go into spontaneous labor w/i 24 hrs of PROM. If spontaneous labor does not ensue, there is increased risk of what?
Chorioamnionitis
(infection of chorion/ amnion/ both)
What complications are a/w PROM? (4)
Preterm labor
Cord prolapse
Placental abruption
Intrauterine infection
Preterm premature rupture of membranes (PPROM) is defined as PROM that occurs when?
Before 37 wks gestation