3

Question 1

What do you need to evaluate risk?

Answer 1

numerator: how many ppl w/ condition

Denominator: How many ppl could experience condition (ex: population)

Question 2

Relative risk

=1

>1

<1

Answer 2

Question 3

Whatis absolute risk?

Answer 3

with condition in group/ # people in group

Question 4

What is absolute benefit/ absolute risk reduction/risk difference (all mean the same thing)

Answer 4

Absolute risk of control group- absolute risk of experimental group

Absolute risk reduction= used to show risks b/c seems smaller

Question 5

Relative benefit (AKA risk reduction AKA relative risk reduction)

Answer 5

absolute benefit/placebo groups absolute risk

Question 6

Odds

Answer 6

Number w/ event, number without event (not a percent)

Question 7

Odds ratio

Answer 7

Odds of event in exposed group/odds of event in unexposed group

Question 8

Phases of drug development

Answer 8

Discovery

Pre-clinical (animal testing)

Phase 1 Trial (first in humans, find safe dose and safety outcomes)

Phase II trials (first look at efficacy)

Phase III trials (RCTs- determine efficacy/harm)

Phase IV trials (FDA)

Question 9

alpha level

Answer 9

a level= chance we reject null when the null is actually true (type 1 error)

p<alpha></alpha>

<p>p&gt;alpha= null is NOT rejected</p>

</alpha>

Question 10

What is effect size?

Answer 10

mean difference/pooled standard deviation

0. 2= small effect
1. 5= medium
2. 8= large

Question 11

r value

Answer 11

r= correlation coefficient

ranges -1 to 1

0=no relationship

+1= perfect positive linear relationship

-1= perfect negative linear relationship

Question 12

What is regression?

Answer 12

r^2 (r squared)= the amount of variation in the data that is explained by the regression

Question 13

p<alpha>
</alpha>

Answer 13

REJECT the null hypothesis