3/7/14 Skin Cancer Slide Review Flashcards
A 60yo female presents with the following lesion on the leg and states “I just want it off there asap”, which of the following would likely be the most reasonable treatment option?
A.EDC
B.Photodynamic Therapy
C.Mohs surgery
D.Liquid nitrogen
E.Vismodigeb
A 60yo female presents with the following lesion on the leg and states “I just want it off there asap”, which of the following would likely be the most reasonable treatment option?
A.EDC
B.Photodynamic Therapy
C.Mohs surgery
D.Liquid nitrogen
E.Vismodigeb
•EDC offers a very good balance of cure rate and convenience for treatment of low risk tumors
Which of the following is incorrect regarding melanoma?
- Is UV related
- Is increasing in incidence
- Site of primary tumor is always in the skin
- Occurs in ~1 in 50 Caucasians
Which of the following is incorrect regarding melanoma?
- Is UV related
- Is increasing in incidence
•Site of primary tumor is always in the skin
•Occurs in ~1 in 50 Caucasians
An 80yo, heavily sun damaged male, presents for treatment of numerous clinically diagnosed ak’s on the face. You offer all the following as reasonable treatment options except:
A.3 weeks of topical imiquimod
B.1 or more sessions of photodynamic therapy
C.Cryotherapy of the largest scaliest lesions
D.Aggressive treatment with lac-hydrin to reduce scaling
An 80yo, heavily sun damaged male, presents for treatment of numerous clinically diagnosed ak’s on the face. You offer all the following as reasonable treatment options except:
A.3 weeks of topical imiquimod
B.1 or more sessions of photodynamic therapy
C.Cryotherapy of the largest scaliest lesions
D.Aggressive treatment with lac-hydrin to reduce scaling
Because this lesion requires more treatment than just removal of scale
Which factor is most predictive of metastasis and therefore survival in melanoma?
A.Location
B.Breslow Depth
C.Duration of lesion
D.Width of lesion
E.Pagetoid spread
Which factor is most predictive of metastasis and therefore survival in melanoma?
A.Location
B.Breslow Depth
C.Duration of lesion
D.Width of lesion
E.Pagetoid spread
•Breslow’s depth has been shown to correlate most closely with metastatic risk and survival
Of the ABCDE’s for melanoma screening which one likely has the most prognostic significance?
- A
- B
- C
- D
- E
Of the ABCDE’s for melanoma screening which one likely has the most prognostic significance?
- A (Asymmetry)
- B (Border)
- C (Color)
- D (Diameter)
•E (Evolution)
Where is melanoma most commonly found on women?
A.Head/Neck
B.Trunk
C.Arms
D.Legs
E.Palms/Soles
Where is melanoma most commonly found on women?
A.Head/Neck
B.Trunk
C.Arms
D.Legs
E.Palms/Soles
A 76yo male patient presents with the following lesion. He requests the treatment option with the highest cure rate but also wants minimal scarring. You recommend which of the following treatments:
A.EDC
B.Photodynamic Therapy
C.Mohs surgery
D.Liquid nitrogen
E.vismodigeb
A 76yo male patient presents with the following lesion. He requests the treatment option with the highest cure rate but also wants minimal scarring. You recommend which of the following treatments:
A.EDC
B.Photodynamic Therapy
C.Mohs surgery
D.Liquid nitrogen
E.vismodigeb
•Mohs surgery offers both the highest cure rate as well as tissue sparing
A 18yo female comes to your office recently heard tanning may not be good for you. You tell her all of the following except:
A.UV is classified as a class 1 carcinogen, the highest designation
B.There is no way to tan the skin without damaging the skin
C.A few minutes of sunlight each day is a good way to get some vitamin D
D.While using good sun protection measures, taking Vit D supplement can be a good idea
E.UV, especially UVA, prematurely ages the skin
A 18yo female comes to your office recently heard tanning may not be good for you. You tell her all of the following except:
A.UV is classified as a class 1 carcinogen, the highest designation
B.There is no way to tan the skin without damaging the skin
C.A few minutes of sunlight each day is a good way to get some vitamin D
D.While using good sun protection measures, taking Vit D supplement can be a good idea
E.UV, especially UVA, prematurely ages the skin
•Unprotected sun exposure is a unmeasured, difficult to quantify and potentially dangerous way to get Vit D. Take a supplement and eat Vit D rich foods
Which of the following regarding melanoma is NOT true?
A.1:50 fair skin people will have melanoma
B.Darker skinned individuals have low to almost no risk of melanoma due to built it melanocytic UV protection
C.Melanoma mortality rate is increasing
D.Melanoma incidence is increasing
Which of the following regarding melanoma is NOT true?
A.1:50 fair skin people will have melanoma
B.Darker skinned individuals have low to almost no risk of melanoma due to built it melanocytic UV protection
C.Melanoma mortality rate is increasing
D.Melanoma incidence is increasing
•Although innate melanin production in darker skin does afford UV protection the prevalence of melanoma is still ~0.1%
A 17yo Caucasian female comes asking about her risk of melanoma, you counsel her on all of the following except:
A.It is critical to monitor all of her nevi as over 90% of melanoma arise from pre-existing nevi
B.Stop tanning bed use as this has been strongly linked to melanoma incidence
C.Her history of intermittent sunburns on vacation as a child has already increased her chance of developing melanoma
D.Her risk for melanoma is more similar to an adult rather than a child
A 17yo Caucasian female comes asking about her risk of melanoma, you counsel her on all of the following except:
A.It is critical to monitor all of her nevi as over 90% of melanoma arise from pre-existing nevi
B.Stop tanning bed use as this has been strongly linked to melanoma incidence
C.Her history of intermittent sunburns on vacation as a child has already increased her chance of developing melanoma
D.Her risk for melanoma is more similar to an adult rather than a child
•There is about a 50/50 incidence of melanoma occurring from within a nevus versus normal appearing skin
A 24yo woman who’s mother was recently diagnosed and treated for BCC comes to your office asking for advice regarding skin cancer prevention. You recommend all of the following except:
A.Avoid outdoor activities from the hours of 10am till 2pm
B.Regular use of sunscreen when outdoors and daily
C.Use tanning beds only sparingly such as for building up a base tan prior to a planned vacation
D.Seek shade structures when outdoors
E.Use of light loose clothing, hat and sunglasses
A 24yo woman who’s mother was recently diagnosed and treated for BCC comes to your office asking for advice regarding skin cancer prevention. You recommend all of the following except:
A.Avoid outdoor activities from the hours of 10am till 2pm
B.Regular use of sunscreen when outdoors and daily
C.Use tanning beds only sparingly such as for building up a base tan prior to a planned vacation
D.Seek shade structures when outdoors
E.Use of light loose clothing, hat and sunglasses
The gene product that is mutated 30-50% of the time in familial variant of this tumor:
A.P16
B.P14
C.Brca2
D.Tsg101
E.P53
The gene product that is mutated 30-50% of the time in familial variant of this tumor:
A.P16
B.P14
C.Brca2
D.Tsg101
E.P53
Patient “V” has been diagnosed with melanoma, which type is the most likely?
A.Superficial spreading
B.Acral lentigenous
C.Nodular
D.Lentigo Maligna
E.Spitzoid
Patient “V” has been diagnosed with melanoma, which type is the most likely?
A.Superficial spreading
B.Acral lentigenous
C.Nodular
D.Lentigo Maligna
E.Spitzoid
•acral lentiginous melanoma is most common in darker skin types
What percentage of a person’s lifetime sun exposure is already had by age 18?
A.
B.60-70
C.70-80
D.80-90
E.>90
What percentage of a person’s lifetime sun exposure is already had by age 18?
A.
B.60-70
C.70-80
D.80-90
E.>90
Newer data suggests ~25%
A patient with the following lesion presents to your office and wants to know how he got skin cancer in this location. You explain it is related to:
A.Sexual activity
B.Tanning bed use
C.Friction
D.Inappropriate use of a topical ointment
A patient with the following lesion presents to your office and wants to know how he got skin cancer in this location. You explain it is related to:
A.Sexual activity
B.Tanning bed use
C.Friction
D.Inappropriate use of a topical ointment
•Bowenoid papulosis is SCCis related to HPV infection
When discussing this infants skin condition, you counsel the parents:
A.This is a completely benign condition
B.The pigmentation will typically resolve by the age of 10
C.The depigmented areas are at a significantly higher risk of melanoma
D.He should be monitored regularly as the risk of melanoma is up to 20%
When discussing this infants skin condition, you counsel the parents:
A.This is a completely benign condition
B.The pigmentation will typically resolve by the age of 10
C.The depigmented areas are at a significantly higher risk of melanoma
D.He should be monitored regularly as the risk of melanoma is up to 20%
