3 Flashcards

1
Q

Bisphosphonates

A

get into bone and incapacitate osteolclast - reduce bone resorption.

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2
Q

Paget’s disease treatment, hypercalcemia, osteoporosis, metastatic bone diesease

A

bisphosphonates

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3
Q

NSAID

A

nonsteroidal anti inflammatory drugs

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4
Q

NSAIDS inhibit

A

biosynth and release of prostaglandins in cells

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5
Q

NSAID side effects

A

gastrointestinal ulceration, allergic reactions, gastrointestinal and renal toxicity

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6
Q

—— reduce gingival inflammation, but have modest effects on attachment

A

NSAIDS

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7
Q

Bisphosphonates side effects

A

osteomalacia, allergic reactions

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8
Q

—— modest effect on bone density, none on attachment loss

A

bisphosphonates

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9
Q

Periostat

A

low dose of doxycycline hyclate - 20 1 pill daily for 3 months - tetracycline related therapy

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10
Q

——- concentrates in GCF and uses cementum as reservoir

A

periostat

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11
Q

——- can increase attachment levels

A

Periostat

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12
Q

NSAIDS not recommended for perio disease treatment due to

A

possible site effects

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13
Q

Controlled delivery for drugs is beneficial because

A

rate control, active over multiple days, active only at site, high concentrations can be used, low overall dose, applied by therapist.

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14
Q

Fibers had to be

A

removed after use

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15
Q

Carriers for injectable systems are

A

PLA, PLGA (slow release)

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16
Q

Collagen gel carrier with chlorhexidine as active material

A

periochip

17
Q

Co polymer carrier with doxycycline as active material

A

atridox

18
Q

Like a sand or salt

A

arestin

19
Q

Slight to moderate perio patients with limited sites that are unresponsive to non-surgical therapy

A

Indicated for local antibiotic.

20
Q

Local antibiotic delivery should be considered as ———– therapy to fSRP for limited sites with _—— probing depths

A

adjunctive

> =5mm

21
Q

Allergies to specific antimicrobial reagent
Several sites/mouth with residual periodontal pockets following SRP
Applications without performing SRP

A

contraindications for local antimicrobial delivery

22
Q

Root planing opens up ——- where bacteria can live

A

dentinal tubules