3-6 Cytokines in Inflammation Flashcards
1
Q
What cells release TNF
A
- Macrophages
- mast cells
- T Lymphocytes
2
Q
What does TNF do
A
-Stimulates expression of adhesion molecules and other cytokines
3
Q
What cells release IL-1
A
- Macrophages
- endothelial cells
- some epithelial cells
4
Q
What does IL-1 do
A
- Similar to TNF
- fever
5
Q
What cells release IL-6
A
macrophages
6
Q
What does IL-6 do
A
systemic effects in acute phase response
7
Q
What cells release IL-17
A
T lymphoctyes
8
Q
What does IL-17 do
A
Recruits neutrophils and monocytes
Acute and Chronic
9
Q
What cells release IL-12
A
- Dendritic cells
- macrophages
10
Q
What does IL-12 do
A
- Increased production of IFN-Ɣ
- Chronic Inflammation
11
Q
What cells release IFN-Ɣ
A
- T lymphocytes
- NK Cells
12
Q
What does IFN-Ɣ do
A
Activation of M1 type Macrophages
