3/24 Key Features - Corbett Flashcards

dx: tracheoesophageal fistula
* issue with TE membrane
also cardio anomalies
difficulty swallowing solids and liquids…

motility vs mechanical?





GERD complications



types of esoph cancer
location
risk factors
1. squamous cell carcinoma
- upper 1/3
- tobacco, alcohol
2. adenocarcinoma
- lower 2/3
- smoking, tobacco, GERD, obesity

Schatzki ring

pill esophagitis
**K, bisphosphonates are common culprits
assoc w odynophagia and retrosternal chest pain

duodenal atresia
pyloric stenosis
malrotation of gut
mix and match





chronic diarrhea

loose stools, incr stool frequency, urgency
chronic is over 4 weeks
- most diarrhea is acute/self-limiting → due to infection
- immunocompetent patients? acute usually resolves within 1-4wk

tropical sprue
- have to have lived in a place for a few weeks/months
- villi atrophied but not flat
*

SIBO
what is it
causes
effects

what prevents SIBO from occuring normally?
- gastric acid/bile destroy bacteria
- proteolytic enzymes destroy bacteria
- intact ileocecal valve and anterograde motility keep things moving FORWARD
- secretory IgA in GI tract prevents bacterial prolif
sooo, what are etiologies of SIBO?
- functional motility disorders (ex. IBS)
- metabolid disorders (ex. DM → autonomic neuropathy)
- anatomic disorders (surgery, blind loop, strictures)
- immune disorders (IgA def)
what is the outcome of SIBO?
- bacteria deconjugate bile acids too early →
- fat malabsorption/vitamind def
- enterocyte injury (by bile acids)

lactulose breath test
double peak if SIBO
