3/15 UWORLD test # 43 Flashcards
Q 1. Where does N.menigitidis localize? What structure of bacteria is required for this?
- nasopharynx mucosal surface
- bacterial pili (fimbriae) mediates its attachment to mucosal epithelium of nasopharynx
Q 4. middle third of rectum drain into what lymph node? what approximate portion of rectum is above or below pectinate line?
internal iliac lymph node
down to lower third drains to internal iliac lymph node
*pectinate line is pretty below (like just lower third)
Q 5. Apart from its use for anticonvulsant, valporate can also be used for treatment of what diseases (2)?
- bipolar disorder
- migrane prophylaxis
Q 5. Apart from its use for anticonvulsant, topiramate can be used for what?
prevention of migraine
- like valporate!
Q 6. Presentation of maturity onset diabetes of the young (MODY)? Mutation on which enzyme is associated with it?
atypical presentation, thin type 2 diabetes-like: hyperglycemia that worsens with pregnancy induced insulin resistance
- mutation on glucokinase is associated with it.
Q 7. compare pathophysiology of man infertility in cystic fibrosis vs. Kartagener syndrome
Cystic Fibrosis: absence of vas deferans
Kartagener: immobile sperm
Q 8. diagnosis criteria of premature ejaculation? What psychiatric condition is associated with it?
ejaculation/ loss of orgasm in LESS THAN ONE MINUTE
of penetration for more than 6 months
- anxiety
patient often do not have issue with premature ejaculation during masturbation. It is anxiety that triggers it.
Q 9. Which step is required prior to admission for advance care?
asking whether patient has advanced directives
Q 10. kidney transplant rejection: acute rejection
- time period?
- histologic finding
- less than 6 months
- dense interstitial lymphocytic infiltrate
Q 10. kidney transplant rejection: chronic rejection
- time period?
- histologic finding
- months to years (more than 6 months)
- obliterative vascular FIBROSIS
Q 10. kidney transplant rejection: hyperacute rejection
- time period?
- histologic finding
- within minutes
- iscehmia/ necrosis
Q 12. Phenelzine: mechanism of action?
MOA inhibitor, non-selective: both MOA-A and MOA-B
Q 14. Describe morphologic of each spinal cord section
- cervical
- Thoracic
- lumbar
- sacral
UWORLD TEST # 43 - Q 14.
Q 15. glomerulonephropathy: immune deposits
- subendothelial (2)
- mesangial (1)
- intramembrane (1)
- subepithelial (2)
- subendothelial: - proliferative
1. type 1 membrenoproliferative
2. diffuse proliferative - mesangial: IgA nephropathy
- intramembrane: type 2 membrenproliferative
- subepithelial: - weried morphologies
1. PSGN: bumps/humps
2. membranous nephropathy: dome/spike
Q 17. lactose non-fermenting, oxidase negative, non-motile gram negative bacteria
- what is this bug?
- what is virulence factor?
- Salmonella
- Samlonella has special capsule called Vi antigen. This antigen prevents phagocytosis & OPSONIZATION